当归治疗糖尿病肾病的作用机制及其研究进展
Mechanism and Research Progress of Angelica sinensis in Treating Diabetic Nephropathy
DOI: 10.12677/ACM.2023.132270, PDF,   
作者: 张忠绅, 张 娜*：黑龙江中医药大学，黑龙江 哈尔滨
关键词: 当归；糖尿病肾病；研究进展；Angelica sinensis； Diabetic Nephropathy； Research Progress
摘要: 糖尿病肾病是糖尿病的一种持续性进展的常见并发症，中药可通过多途径、多靶点减缓肾功能的衰弱，延缓疾病进展。当归是一种具有补血、活血作用的中草药，临床常用来治疗月经异常等其他女性疾病，以其造血、抗氧化与调节人体免疫等作用而闻名。根据最近的动物研究和临床试验可知，当归已被用于治疗糖尿病肾病及其他多种并发症，可减轻患者肾脏组织损伤，进而延缓糖尿病肾病病情进展。本文综述了近年来当归的药理学作用与临床研究进展，并进行系统梳理和归纳分析，以期为当归治疗糖尿病肾病的进一步机制研究和临床应用提供参考。
Abstract: Diabetic nephropathy is a common complication of persistent progression of diabetes. Traditional Chinese medicine can slow down the loss of renal function and prevent the progression of the dis-ease through multiple approaches and multiple targets. Angelica sinensis is a kind of Chinese herb-al medicine with the function of tonifying and promoting blood circulation. It is commonly used to treat menstrual abnormalities and other female diseases in clinic. It is famous for its hematopoietic, antioxidant and immune regulation effects. According to recent animal studies and clinical trials, angelica has been used in the treatment of diabetic nephropathy and its complications, which can reduce the damage of kidney tissue in patients and thus delay the progression of diabetic nephrop-athy. In this paper, pharmacological effects and clinical research progress of Angelica sinensis in recent years were reviewed, and systematic analysis and induction were carried out in order to provide reference for further mechanism research and clinical application of Angelica sinensis in the treatment of diabetic nephropathy.
文章引用：张忠绅, 张娜. 当归治疗糖尿病肾病的作用机制及其研究进展[J]. 临床医学进展, 2023, 13(2): 1952-1956. https://doi.org/10.12677/ACM.2023.132270

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