多个实验指标在急性阑尾炎不同感染程度中诊断价值的研究现状及进展

Research Status and Progress of the Diagnostic Value of Multiple Experimental Indexes in Different Degrees of Acute Appendicitis

摘要: 急性阑尾炎作为目前最常见的急腹症之一，目前急性阑尾炎的诊断主要依靠典型的症状体征、实验室检查及影像学检查，但由于部分患者的症状和体征与病变严重程度不相符，腹部CT和超声检查受到患者腹腔积气及诊断医生经验等因素的影响，准确判断患者病变严重程度也受到一定程度的影响，从而导致治疗时机的延误。国内外大量研究表明白细胞(WBC)、降钙素原(PCT)等多个实验室指标与急性阑尾炎严重程度的诊断密切相关，本文旨在对白细胞(WBC)、降钙素原(PCT)、C反应蛋白(CRP)、白细胞介素-6 (IL-6)、D-二聚体(D-D)、胆红素(BIL)对急性阑尾炎不同感染程度的诊断价值进行综述。

Abstract: Acute appendicitis is one of the most common acute abdominal diseases at present. At present, the diagnosis of acute appendicitis mainly depends on the typical symptoms and signs, laboratory ex-amination and imaging examination. However, because the symptoms and signs of some patients are not consistent with the severity of the disease, abdominal CT and ultrasound examination are affected by factors such as the patient’s abdominal cavity gas accumulation and the experience of the diagnostic doctor, and the accurate judgment of the severity of the disease is also affected to a certain extent. This leads to the delay of treatment time. A large number of studies at home and abroad have shown that many laboratory indicators such as WBC and PCT are closely related to the diagnosis of the severity of acute appendicitis. This article aims to review the diagnostic value of WBC, PCT, CRP, IL-6, D-D and BIL in the diagnosis of acute appendicitis with different degrees of in-fection.