养心通脉方治疗冠心病稳定型心绞痛气虚血瘀证的临床观察研究

Clinical Observation and Research on Yangtongmai Recipe in Treating Stable Angina Pectoris of Coronary Heart Disease with Qi Deficiency and Blood Stasis Syndrome

摘要: 目的：分析养心通脉方联合常规西药对冠心病稳定型心绞痛气虚血瘀证患者的影响。方法：选取2020年6月~2021年12月诊治的冠心病稳定型心绞痛气虚血瘀证患者80例，采用随机分组法，分成对照组与观察组，每组40例。对照组接受常规西药治疗，观察组患者接受养心通脉方联合常规西药治疗。运用血常规、肝肾功能等评价其安全性。比较两组患者西雅图心绞痛量表和中医证候积分。结论：干预前，两组心绞痛严重程度分级、西雅图心绞痛量表和中医证候积分基本相同，差异无统计学意义(P > 0.05)。干预后，参照西雅图心绞痛量表，观察组躯体受限程度(PL)、心绞痛稳定状态(AS)、心绞痛发作情况(AF)、治疗满意程度(TS)均高于对照组，且两组均值差异有统计学意义(P < 0.05)，且观察组在中医证候积分上明显优于对照组(P < 0.05)，两组前后差异比较有统计学意义。结论：养心通脉方能明显改善冠心病稳定型心绞痛气虚血瘀证患者症状，提高生活质量，无明显不良反应。

Abstract: Objective: To analyze the effect of Yangxintongmai Decoction combined with conventional western medicine on stable angina pectoris in patients with qi deficiency and blood stasis syndrome. Methods: A total of 80 patients with stable angina pectoris of qi deficiency and blood stasis syndrome diagnosed and treated from June 2020 to December 2021 were selected and randomized into a control group and an observation group, 40 cases in each one. The control group was treated with conventional western medicine, and the patients in the observation group were treated with Yangxintongmai Decoction combined with conventional western medicine. The safety was evaluated by routine blood test, liver and kidney function test, etc. Two groups were compared with Seattle Angina Pectoris Scale and TCM syndrome score. Conclusion: Before intervention, the severity grade of angina pectoris, Seattle Angina Pectoris Scale and TCM syndrome score in the two groups were basically the same, and the difference was not statistically significant (P > 0.05). After intervention, according to the Seattle Angina Pectoris Scale, the levels of physical limitation (PL), stable angina pectoris (AS), attack of angina pectoris (AF) and treatment satisfaction (TS) in the observation group were higher than those of the control group, and the difference between the two groups was statistically significant (P < 0.05). The TCM syndrome scores of the observation group were significantly better than those of the control group (P < 0.05). The differences between the two groups were statistically significant. Conclusion: Yangxintongmai Decoction can significantly improve the symptoms of patients with stable angina pectoris of qi deficiency and blood stasis syndrome and improve the quality of life without significant adverse reactions.