甲状腺自身免疫对辅助生殖技术结局的影响的研究进展
Progress in Investigating the Impact of Thyroid Autoimmunity on Assisted Reproductive Technology Outcomes
DOI: 10.12677/ACM.2023.132352, PDF,   
作者: 贺宇轩, 腊晓琳*：新疆医科大学第一附属医院生殖中心，新疆 乌鲁木齐
关键词: 甲状腺自身免疫；不孕；辅助生殖技术；妊娠结局；Thyroid Autoimmunity； Infertility； Assisted Reproductive Technology； Pregnancy Outcome
摘要: 甲状腺自身免疫是育龄期女性最常见的自身免疫性疾病，甲状腺自身性免疫(thyroid autoimmunity, TAI)是以单纯甲状腺自身抗体(thyroid autoantibodies, TAA)阳性为特征。大量研究表明，甲状腺自身抗体阳性与不孕不育和流产有关，但目前尚不清楚其相关机理和因果关系。但也有研究人员指出，单纯的甲状腺自身抗体阳性并不足以导致妊娠结局不佳的辅助生殖。文章总结了甲状腺自身免疫对辅助生殖技术结局的影响，希望今后能有更多的随机对照研究，明确胚胎移植前确定自身免疫性甲状腺疾病的存在，并对接受ART治疗的不孕不育女性进行一定的预处理的必要性。
Abstract: Thyroid autoimmunity is the most common autoimmune disease in women of childbearing age. Thyroid autoimmunity is characterized by only positive thyroid autoantibody. Numerous studies have shown that thyroid autoantibody positivity is associated with infertility and abortion, but the related mechanism and causality relationship are still unclear. But some researchers point out that positive thyroid autoantibodies alone is not enough to lead to assisted reproduction with poor pregnancy outcomes. This paper summarizes the influence of thyroid autoimmunity on the outcome of assisted reproductive technology, hoping that more randomized controlled studies in the future can clarify the existence of autoimmune thyroid disease before embryo transfer, and the necessity of certain pretreatment of infertile women receiving ART.
文章引用：贺宇轩, 腊晓琳. 甲状腺自身免疫对辅助生殖技术结局的影响的研究进展[J]. 临床医学进展, 2023, 13(2): 2500-2504. https://doi.org/10.12677/ACM.2023.132352

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