miRNA在胃癌及结直肠癌中的研究进展
Research Progress of miRNA in Gastric Cancer and Colorectal Cancer
DOI: 10.12677/ACM.2023.132405, PDF,   
作者: 马海明*, 马新福:青海大学附属医院,青海 西宁
关键词: miR-21癌症胰腺肝脏胃肠道消化系统miR-21 Cancer Pancreas Liver Gastrointestinal Tract Digestive System
摘要: 微小核糖核酸是小的非编码核糖核酸。它们可以调节靶基因的表达,因此,它们的失调显著促进了癌症的发展。越来越多的证据表明,miRNAs可以用作癌症生物标志物。miRNA作为诊断和预后生物标志物的作用及其治疗应用已被广泛研究。本文就miRNA在胃癌及结直肠癌中促癌机制的研究进展作一综述。
Abstract: MicroRNA is a small noncoding RNA. They can regulate the expression of target genes, so their dis-order significantly promotes the development of cancer. More and more evidence shows that miR-NAs can be used as cancer biomarkers. The role of miRNA as a biomarker for diagnosis and progno-sis and its therapeutic application have been widely studied. In this paper, the research progress of miRNA in promoting cancer in gastric cancer and colorectal cancer is reviewed.
文章引用:马海明, 马新福. miRNA在胃癌及结直肠癌中的研究进展[J]. 临床医学进展, 2023, 13(2): 2866-2872. https://doi.org/10.12677/ACM.2023.132405

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