我国声带麻痹常见病因的Meta分析

Meta Analysis of Common Causes of Vocal Cord Paralysis in China

摘要: 目的：系统评价我国声带麻痹常见病因。方法：使用计算机检索中国学术期刊全文数据库(CNKI)、万方数据库、中国生物医学文献光盘数据库(CBM)、维普信息资源系统、中国科学引文数据库(CSCD)中有关声带麻痹病因的相关文献，检索时间从2002年1月至2022年12月，采用R软件对符合条件的文献进行荟萃分析。结果：共纳入8个随机对照实验，合计887例患者。Meta分析结果显示：肿瘤、医源性损伤、特发性病因、感染、创伤的病因构成比(95% CI)分别是33.34% (23.62%~43.06%)、26.15% (14.73%~37.58%)、12.28% (9.05%~15.51%)、10.11% (6.50%~13.72%)、9.11% (5.38%~12.83%)。结论：肿瘤是我国声带麻痹的最主要病因，医源性损伤、特发性病因、感染、创伤也是常见的病因。

Abstract: Objective: To systematically evaluate the common causes of vocal cord paralysis in China. Methods: The relevant literatures about the etiology of vocal cord paralysis in Chinese academic Journal full-text Database (CNKI), Wanfang Database, Chinese Biomedical Literature CD-ROM Database (CBM), VIP Information Resource system and China Science Citation Database (CSCD) were searched by computer from January 2002 to December 2022. The qualified literatures were meta-analyzed by R software. Results: A total of 887 patients were enrolled in 8 randomized controlled trials. The results of Meta analysis showed that the etiological constituent ratios (95% CI) of tumor, iatrogenic injury, idiopathic etiology, infection and trauma were 33.34% (23.62%~43.06%), 26.15% (14.73%~37.58%), 12.28% (9.05%~15.51%), 10.11% (6.50%~13.72%) and 9.11% (5.38%~12.83%), respectively. Conclusion: Tumor is the main cause of vocal cord paralysis in China, and iatrogenic injury, idiopathic etiology, infection and trauma are also common causes.