富血小板血浆联合治疗膝关节骨性关节炎进展

Progress of Combined Platelet-Rich Plasma Therapy for Knee Osteoarthritis

摘要: 膝关节骨性关节炎在肌肉骨骼疾病中最为常见，中老年人为好发群体。有症状的患者主诉有疼痛和活动能力障碍。治疗包括物理治疗、口服药物治疗、关节内药物注射治疗、微创介入治疗、手术治疗等。这些疗法旨在控制疼痛和炎症，改善活动能力和功能，而新的基于自体富血小板血浆关节腔注射的疗法有促进骨和软骨再生修复的潜力，成为越来越受到关注的生物产品。因此，本文对富血小板血浆联合治疗方案的临床疗效、优缺点等方面进行综述。

Abstract: Knee osteoarthritis is the most common in musculoskeletal diseases, middle-aged and elderly people are prone to the group. Symptomatic patients complain of pain and mobility problems. Treatment includes physical therapy, oral drug therapy, intra-articular drug injection therapy, minimally invasive interventional therapy, and surgical therapy. These therapies are designed to control pain and inflammation and improve mobility and function, while new therapies based on autologous platelet-rich plasma injection into the articular cavity have the potential to promote bone and cartilage regeneration and repair, becoming a biological product of increasing interest. Therefore, this paper reviews the clinical efficacy, advantages and disadvantages of combined platelet-rich plasma therapy.