长链非编码RNA对心脏成纤维细胞功能的研究进展
Advances in the Study of Long Non-Coding RNA on Cardiac Fibroblast Function
DOI: 10.12677/ACM.2023.133453, PDF,    科研立项经费支持
作者: 孔开元:济宁医学院临床医学院,山东 济宁;陈雪英, 刘立新*:济宁医学院附属医院心内科,山东 济宁
关键词: 长链非编码RNA心脏成纤维细胞心脏重构Long Non-Coding RNA Cardiac Fibroblasts Cardiac Remodeling
摘要: 心脏成纤维细胞参与心脏各种损伤的修复,可以维持心脏结构和功能的完整。非编码RNA参与许多疾病的进展,已经成为进一步了解成纤维细胞的新方向,其中长链非编码RNAs (Long Non-Coding RNAs, LncRNAs)数量丰富、种类众多,本文总结通过调控心脏成纤维细胞参与心脏重构的长链非编码RNAs,并简述其作用机制。
Abstract: Cardiac fibroblasts are involved in the repair of various cardiac injuries and can maintain the structural and functional integrity of the heart. The involvement of non-coding RNA in the pro-gression of many diseases has become a new direction for further understanding of fibroblasts, among which long non-coding RNAs (LncRNAs) are abundant and diverse. In this paper, we sum-marize the long non-coding RNAs involved in cardiac remodeling through regulation of cardiac fi-broblasts, and briefly describe their mechanisms of action.
文章引用:孔开元, 陈雪英, 刘立新. 长链非编码RNA对心脏成纤维细胞功能的研究进展[J]. 临床医学进展, 2023, 13(3): 3184-3193. https://doi.org/10.12677/ACM.2023.133453

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