|
[1]
|
Kelly, T., Yang, W., Chen, C.-S., Reynolds, K. and He, J. (2008) Global Burden of Obesity in 2005 and projections to 2030. International Journal of Obesity, 32, 1431-1437. [Google Scholar] [CrossRef] [PubMed]
|
|
[2]
|
Qatanani, M. and Lazar, M.A. (2007) Mechanisms of Obesity-Associated Insulin Resistance: Many Choices on the Menu. Genes & De-velopment, 21, 1443-1455. [Google Scholar] [CrossRef] [PubMed]
|
|
[3]
|
Chan, P.-C., et al. (2018) Targeted Inhibition of CD74 Attenuates Adipose COX-2-MIF-Mediated M1 Macrophage Polarization and Retards Obesity-Related Adipose Tissue Inflammation and Insulin Resistance. Clinical Science, 132, 1581-1596. [Google Scholar] [CrossRef]
|
|
[4]
|
Ouchi, N., Parker, J.L., Lugus, J.J. and Walsh, K. (2011) Adipokines in Inflammation and Metabolic Disease. Nature Reviews Immunology, 11, 85-97. [Google Scholar] [CrossRef] [PubMed]
|
|
[5]
|
Weisberg, S.P., et al. (2003) Obesity Is Associated with Macrophage Accu-mulation in Adipose Tissue. Journal of Clinical Investigation, 112, 1796-1808. [Google Scholar] [CrossRef]
|
|
[6]
|
Hotamisligil, G.S. (2017) Foundations of Immunometabolism and Implica-tions for Metabolic Health and Disease. Immunity, 47, 406-420. [Google Scholar] [CrossRef] [PubMed]
|
|
[7]
|
Lumeng, C.N., Bodzin, J.L. and Saltiel, A.R. (2007) Obesity Induces a Phenotypic Switch in Adipose Tissue Macrophage Polarization. Journal of Clinical Investigation, 117, 175-184. [Google Scholar] [CrossRef]
|
|
[8]
|
Lee, Y.H., et al. (2005) Microarray Profiling of Isolated Ab-dominal Subcutaneous Adipocytes from Obese vs Non-Obese Pima Indians: Increased Expression of Inflamma-tion-Related Genes. Diabetologia, 48, 1776-1783. [Google Scholar] [CrossRef] [PubMed]
|
|
[9]
|
Mueller, C.K. and Schultze-Mosgau, S. (2011) Histomorphomet-ric Analysis of the Phenotypical Differentiation of Recruited Macrophages Following Subcutaneous Implantation of an Allogenous Acellular Dermal Matrix. International Journal of Oral & Maxillofacial Surgery, 40, 401-407. [Google Scholar] [CrossRef] [PubMed]
|
|
[10]
|
Fujiu, K., Manabe, I. and Nagai, R. (2011) Renal Collecting Duct Epithelial Cells Regulate Inflammation in Tubulointerstitial Damage in Mice. Journal of Clinical Investigation, 121, 3425-3441. [Google Scholar] [CrossRef]
|
|
[11]
|
Galès, A., et al. (2010) PPARγ Controls Dectin-1 Expression Required for Host Antifungal Defense against Candida albicans. PLOS Pathogens, 6, e1000714. [Google Scholar] [CrossRef] [PubMed]
|
|
[12]
|
Calandra, T., Bernhagen, J., Mitchell, R.A. and Bucala, R. (1994) The Macrophage Is an Important and Previously Unrecognized Source of Macrophage Migration Inhibitory Factor. Journal of Experimental Medicine, 179, 1895-1902. [Google Scholar] [CrossRef] [PubMed]
|
|
[13]
|
Finucane, O.M., Reynolds, C.M., McGillicuddy, F.C. and Roche, H.M. (2012) Insights into the Role of Macrophage Migration Inhibitory Factor in Obesity and Insulin Resistance. Pro-ceedings of the Nutrition Society, 71, 622-633. [Google Scholar] [CrossRef]
|
|
[14]
|
Ghanim, H., et al. (2004) Circulating Mononuclear Cells in the Obese Are in a Proinflammatory State. Circulation, 110, 1564-1571. [Google Scholar] [CrossRef]
|
|
[15]
|
Dandona, P., et al. (2004) Increased Plasma Concen-tration of Macrophage Migration Inhibitory Factor (MIF) and MIF mRNA in Mononuclear Cells in the Obese and the Suppressive Action of Metformin. The Journal of Clinical Endocrinology & Metabolism, 89, 5043-5047. [Google Scholar] [CrossRef] [PubMed]
|
|
[16]
|
Sakaue, S., et al. (2006) Promoter Polymorphism in the Macrophage Migration Inhibitory Factor Gene Is Associated with Obesity. International Journal of Obesity, 30, 238-242. [Google Scholar] [CrossRef] [PubMed]
|
|
[17]
|
Vozarova, B., et al. (2002) Plasma Concentrations of Macrophage Mi-gration Inhibitory Factor Are Elevated in Pima Indians Compared to Caucasians and Are Associated with Insulin Re-sistance. Diabetologia, 45, 1739-1741. [Google Scholar] [CrossRef] [PubMed]
|
|
[18]
|
Church, T.S., et al. (2005) Obesity, Macrophage Migration Inhib-itory Factor, and Weight Loss. International Journal of Obesity, 29, 675-681. [Google Scholar] [CrossRef] [PubMed]
|
|
[19]
|
Herder, C., et al. (2008) Effect of Macrophage Migration Inhibitory Factor (MIF) Gene Variants and MIF Serum Concentrations on the Risk of Type 2 Diabetes: Results From the MONICA/KORA Augsburg Case-Cohort Study, 1984-2002. Diabetologia, 51, 276-284. [Google Scholar] [CrossRef] [PubMed]
|
|
[20]
|
Aslani, S., Hossein-Nezhad, A., Maghbooli, Z., Mirzaei, K. and Karimi, F. (2011) Genetic Variation in Macrophage Migration Inhibitory Factor Associated with Gestational Diabetes Mellitus and Metabolic Syndrome. Hormone and Metabolic Research, 43, 557-561. [Google Scholar] [CrossRef] [PubMed]
|
|
[21]
|
Yilmaz, Ö., et al. (2012) Macrophage Migration-Inhibitory Factor Is Elevated in Pregnant Women with Gestational Diabetes Mellitus. Gynecological Endocrinology, 28, 76-79. [Google Scholar] [CrossRef] [PubMed]
|
|
[22]
|
Stark, R., Ashley, S.E. and Andrews, Z.B. (2013) AMPK and the Neuroendocrine Regulation of Appetite and Energy Expenditure. Molecular and Cellular Endocrinology, 366, 215-223. [Google Scholar] [CrossRef] [PubMed]
|
|
[23]
|
Cantó, C. and Auwerx, J. (2010) AMP-Activated Protein Kinase and Its Downstream Transcriptional Pathways. Cellular and Molecular Life Sciences, 67, 3407-3423. [Google Scholar] [CrossRef] [PubMed]
|
|
[24]
|
Steinberg, G.R. and Kemp, B.E. (2009) AMPK in Health and Disease. Physiological Reviews, 89, 1025-1078. [Google Scholar] [CrossRef] [PubMed]
|
|
[25]
|
Salminen, A., Hyttinen, J.M. and Kaarniranta, K. (2011) AMP-Activated Protein Kinase Inhibits NF-κB Signaling and Inflammation: Impact on Healthspan and Lifespan. Journal of Molecular Medicine, 89, 667-676. [Google Scholar] [CrossRef] [PubMed]
|
|
[26]
|
Lage, R., Diéguez, C., Vidal-Puig, A. and López, M. (2008) AMPK: A Metabolic Gauge Regulating Whole-Body Energy Homeostasis. Trends in Molecular Medicine, 14, 539-549. [Google Scholar] [CrossRef] [PubMed]
|
|
[27]
|
Park, S., Kim, D.S., Kang, S. and Shin, B.K. (2014) Chronic Activation of Central AMPK Attenuates Glucose-Stimulated Insulin Secretion and Exacerbates Hepatic Insulin Re-sistance in Diabetic Rats. Brain Research Bulletin, 108, 18-26. [Google Scholar] [CrossRef] [PubMed]
|
|
[28]
|
Maury, E. and Brichard, S.M. (2010) Adipokine Dysregu-lation, Adipose Tissue Inflammation and Metabolic Syndrome. Molecular and Cellular Endocrinology, 314, 1-16. [Google Scholar] [CrossRef] [PubMed]
|
|
[29]
|
Steinberg, G.R., et al. (2006) Tumor Necrosis Factor α-Induced Skeletal Muscle Insulin Resistance Involves Suppression of Amp-Kinase Signaling. Cell Metabolism, 4, 465-474. [Google Scholar] [CrossRef] [PubMed]
|
|
[30]
|
Lan, F., Cacicedo, J.M., Ruderman, N. and Ido, Y. (2008) SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1. Possible Role in AMP-Activated Protein Kinase Activation. Journal of Biological Chemistry, 283, 27628-27635. [Google Scholar] [CrossRef]
|
|
[31]
|
Zhou, D., et al. (2014) Macrophage Polarization and Function with Emphasis on the Evolving Roles of Coordinated Regulation of Cellular Signaling Pathways. Cellular Signalling, 26, 192-197. [Google Scholar] [CrossRef] [PubMed]
|
|
[32]
|
Dhanasekaran, D.N. and Reddy, E.P. (2008) JNK Signaling in Apoptosis. Oncogene, 27, 6245-6251. [Google Scholar] [CrossRef] [PubMed]
|
|
[33]
|
Tesz, G.J., et al. (2007) Tumor Necrosis Factor α (TNFα) Stimulates Map4k4 Expression through TNFα Receptor 1 Signaling to c-Jun and Activating Transcription Factor 2. Journal of Bio-logical Chemistry, 282, 19302-19312. [Google Scholar] [CrossRef]
|
|
[34]
|
Radtke, F., MacDonald, H.R. and Tacchini-Cottier, F. (2013) Regu-lation of Innate and Adaptive Immunity by Notch. Nature Reviews Immunology, 13, 427-437. [Google Scholar] [CrossRef] [PubMed]
|
|
[35]
|
Artavanis-Tsakonas, S., Rand, M.D. and Lake, R.J. (1999) Notch Signaling: Cell Fate Control and Signal Integration in Development. Science, 284, 770-776. [Google Scholar] [CrossRef] [PubMed]
|
|
[36]
|
Leidi, M., et al. (2009) M2 Macrophages Phagocytose Rituxi-mab-Opsonized Leukemic Targets More Efficiently than M1 Cells in Vitro. The Journal of Immunology, 182, 4415-4422. [Google Scholar] [CrossRef] [PubMed]
|
|
[37]
|
Sica, A., Schioppa, T., Mantovani, A. and Allavena, P. (2006) Tumour-Associated Macrophages Are a Distinct M2 Polarised Population Promoting Tumour Progression: Potential Targets of Anti-Cancer Therapy. European Journal of Cancer, 42, 717-727. [Google Scholar] [CrossRef] [PubMed]
|
|
[38]
|
Ohishi, K., et al. (2000) Monocytes Express High Amounts of Notch and Undergo Cytokine Specific Apoptosis Following Interaction with the Notch Ligand, Delta-1. Blood, 95, 2847-2854. [Google Scholar] [CrossRef]
|
|
[39]
|
Kopan, R. and Ilagan, M.X. (2009) The Ca-nonical Notch Signaling Pathway: Unfolding the Activation Mechanism. Cell, 137, 216-233. [Google Scholar] [CrossRef] [PubMed]
|
|
[40]
|
Bi, P., et al. (2014) Inhibition of Notch Signaling Promotes Brown-ing of White Adipose Tissue and Ameliorates Obesity. Nature Medicine, 20, 911-918. [Google Scholar] [CrossRef] [PubMed]
|
|
[41]
|
Xu, H., et al. (2012) Notch-RBP-J Signaling Regulates the Transcription Factor IRF8 to Promote Inflammatory Macrophage Polarization. Nature Immunology, 13, 642-650. [Google Scholar] [CrossRef] [PubMed]
|
|
[42]
|
Wang, Y.-C., et al. (2010) Notch Signaling Determines the M1 versus M2 Polarization of Macrophages in Antitumor Immune Responses. Cancer Research, 70, 4840-4849. [Google Scholar] [CrossRef]
|
|
[43]
|
Akbar, D.H. (2003) Effect of Metformin and Sulfonylurea on C-Reactive Protein Level in Well-Controlled Type 2 Diabetics with Metabolic Syndrome. Endocrine, 20, 215-218. [Google Scholar] [CrossRef]
|