老年乳腺癌临床诊疗研究进展
Advances in Clinical Diagnosis and Treatment of Senile Breast Cancer
DOI: 10.12677/ACM.2023.133495, PDF,   
作者: 刘兴维, 曹 朝：新疆医科大学第四临床医学院，新疆 乌鲁木齐；耿中利*：新疆维吾尔自治区中医医院普外二科一组，新疆 乌鲁木齐
关键词: 老年乳腺癌；研究进展；临床特点；综述；Senile Breast Cancer； Research Progress； Clinical Features； Review
摘要: 乳腺癌是一种发病率逐渐升高并且严重威胁女性健康的恶性肿瘤之一，目前乳腺癌治疗策略的临床试验数据主要来源于年轻患者，有关老年乳腺癌的循证治疗依据很少，暂无对于老年乳腺癌患者统一的治疗方案。由于老年患者缺乏对于乳腺癌方面的认知，忽略定期筛查的重要性，或者发现乳房肿块时也不及时就医等情况，所以加强老年女性对于乳腺癌的了解和科普宣教是很有必要的。本文综述了老年乳腺癌临床诊疗的一些研究进展，为老年乳腺癌的防治提供依据。
Abstract: Breast cancer is one of the malignant tumors with increasing incidence and serious threat to women’s health. Currently, clinical trial data of breast cancer treatment strategies mainly come from young patients, while there is little evidence-based treatment basis for elderly breast cancer patients, and there is no unified treatment plan for elderly breast cancer patients. Because elderly patients lack awareness of breast cancer, ignore the importance of regular screening, or do not seek medical attention in time when breast lumps are found, it is necessary to strengthen elderly women’s understanding of breast cancer and popular science education. In this paper, some ad-vances in the clinical diagnosis and treatment of senile breast cancer are reviewed to provide a basis for the prevention and treatment of senile breast cancer.
文章引用：刘兴维, 曹朝, 耿中利. 老年乳腺癌临床诊疗研究进展[J]. 临床医学进展, 2023, 13(3): 3469-3474. https://doi.org/10.12677/ACM.2023.133495

参考文献

[1] Richardson, L.C., Henley, S.J., Miller, J.W., et al. (2016) Patterns and Trends in Age-Specific Black-White Differences in Breast Cancer Incidence and Mortality—United States, 1999-2014. Morbidity and Mortality Weekly Report, 65, 1093-1098. [Google Scholar] [CrossRef] [PubMed]
[2] Fan, L., Strasser-Weippl, K., Li, J.J., et al. (2014) Breast Cancer in China. The Lancet Oncology, 15, e279-e289. [Google Scholar] [CrossRef] 
[3] 王永南, 李文萍, 于海云, 万舰. 老年乳腺癌术后辅助化疗对预后的影响[J]. 岭南现代临床外科, 2017, 17(2): 198-201.
[4] 王祥宇. 老年女性乳腺癌的临床病理特征及预后分析[D]: [硕士学位论文]. 石家庄: 河北医科大学, 2021.
[5] 赵卫红, 徐兵河, 李青, 等. 70岁以上老年女性乳腺癌患者的特点和预后分析[J]. 中华肿瘤杂志, 2006(5): 385-388.
[6] 严珊珊, 王永南. 老年乳腺癌的临床病理特点和预后的特点[J]. 岭南现代临床外科, 2019(6): 689-693.
[7] Gennari, R., Curigliano, G., Rotmensz, N., et al. (2004) Breast Carcinoma in Elderly Women: Features of Disease Presentation, Choice of Local and Systemic Treatments Compared with Younger Postmenopausal Patients. Cancer, 101, 1302-1310. [Google Scholar] [CrossRef] [PubMed]
[8] 蔡建强, 等. 65岁以上老年乳腺癌的治疗和预后[J]. 癌症杂志, 2000, 15(2): 179-183.
[9] 中国抗癌协会乳腺癌专业委员会. 中国抗癌协会乳腺癌诊治指南与规范(2021年版) [J]. 中国癌症杂志, 2021, 31(10): 954-1040.
[10] 李晓红. 紫杉类药物用于老年乳腺癌患者新辅助化疗疗效及不良反应分析[J]. 实用临床医药杂志, 2013, 17(15): 74-76.
[11] 曹原, 高军. 紫杉类药物新辅助治疗老年乳腺癌的疗效及不良反应分析[J]. 实用癌症杂志, 2019, 34(9): 1485-1487.
[12] 黄波, 林建山, 袁园园. 老年乳腺癌治疗中紫杉类药物新辅助治疗的疗效及不良反应[J]. 中国现代药物应用, 2020, 14(17): 188-190.
[13] 谢意程, 张海良. 老年乳腺癌治疗中紫杉类药物新辅助治疗的疗效及不良反应研究[J]. 北方药学, 2022(9): 138-140.
[14] 吕锋, 黄小娥, 鲁科斌. 蒽环类与紫杉类联合新辅助化疗治疗早期或局部晚期乳腺癌的疗效及对患者ER, PR和Her-2的影响[J]. 中国生化药物杂志, 2017, 37(3): 195-197.
[15] 孟凡军, 陈育标, 庄梅生. 早期乳腺癌保留乳房手术后全乳腺大分割与常规分割放疗的疗效和毒副反应比较[J]. 海南医学, 2017, 28(12): 2024-2025.
[16] Gradishar, W.J. and Anderson, B.O. (2020) Breast Cancer, Version 3.2020, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network: JNCCN, 18, 452-478.
[17] 徐兵河. 乳腺癌靶向治疗的临床进展和未来[J]. 中国肿瘤临床, 2017, 44(13): 625-629.
[18] 汪霖. 人类表皮生长因子受体2阳性肿瘤靶向药物研究进展[J]. 实用肿瘤学杂志, 2016, 30(3): 266-270.
[19] Daniels, B., Kiely, B.E., Tang, M., et al. (2019) Trastuzumab Use in Older Patients with HER2-Positive Metastatic Breast Cancer: Outcomes and Treatment Patterns in a Whole-of-Population Australian Cohort (2003-2015). BMC Cancer, 19, 909. [Google Scholar] [CrossRef] [PubMed]
[20] Early Breast Cancer Trialists Collaborative Group (1998) Tamoxifen for Early Breast Cancer: An Overview of the Randomized Trials. The Lancet, 351, 1451-1467. [Google Scholar] [CrossRef] 
[21] 江泽飞, 宋三泰, 孙燕. 乳腺癌内分泌治疗的基本原则和新动向——2006年美国NCCN乳癌内分泌治疗解读[J]. 临床药物治疗杂志, 2006, 4(2): 21-25.

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