孕期女性B族链球菌感染情况分析

Analyze of Group B Streptococcus Infection in Pregnant Women

摘要: 目的：分析孕期妇女生殖道B族链球菌(GBS)的感染情况。方法：选取2021年01月至2021年12月于我院产科门诊就诊的1147例孕期妇女作为研究对象，检测其阴道拭子标本中GBS感染情况，并分析GBS对围产期孕妇的影响。结果：1144例标本中检出GBS阳性41例，检出率为：3.58%。其中，27例妊娠中期妇女(13~27周)标本中检出3例GBS阳性，检出率为11.11%，高于例妊娠晚期妇女(28~41周)标本中GBS阳性的检出率为3.40% (38/1117)，存在显著差异(P < 0.05)；通过对不同年龄组孕期妇女阴道分泌物样本中GBS感染率比较，发现>40岁(9.09%)的检出率最高，明显高于≤25岁(3.80%)、26~30岁(2.70%)、31~35 (3.92%)和36~40岁(3.72%)，且26~30岁组的检出率最低。结论：不同妊娠期、不同年龄组间B族链球菌的带菌率存在一定的差异，但由于GBS感染阳性会诱发早产、胎膜早破、孕妇产褥感染等，甚至会对新生儿的健康造成影响，临床应加强对妊娠晚期妇女GBS检测，对GBS阳性的孕期妇女采取有效措施进行干预治疗。

Abstract: Objective: To analyze the infection of group B streptococcus (GBS) in reproductive tract of pregnant women. Methods: From January 2021 to December 2021, a total of 1147 pregnant women were se-lected as study subjects, GBS from vaginal discharge was detected, and the impact on pregnancy outcome was analyzed. Results: In the 1147cases, 48 cases were GBS positive, the GBS positive rate was 3.58%, and 3 cases were GBS positive among the second trimester (13 to 27 weeks), with a pos-itive rate was 11.11%, which was higher than that of women of in the third trimester (28 to 41 weeks) with a positive rate was 3.40% (38/1117), with significant differences (P < 0.05). The posi-tive rate of GBS in vaginal secretions samples of pregnant women that the age >40 group (9.09%) was the highest in different age groups, which was significantly higher than that ≤ 25 (3.80%), 26~30 (2.70%), 31~35 (3.92%) and 36~40 (3.72%), the detection rate was the lowest in the 26~30 age group. Conclusions: The GBS carrier rates were certain differences in different gestation and age group. But GBS infection positive can cause premature delivery, premature rupture of membranes, puerperal infection of pregnant women, and even affect the health of newborns. So the GBS detec-tion in the late pregnancy is necessary, and effective treatment measures should be taken to treat GBS positive pregnant women.