膀胱及前列腺双原发癌的临床研究进展
Clinical Research Progress of Double Primary Cancers of Bladder and Prostate
DOI: 10.12677/ACM.2023.133584, PDF,   
作者: 凯买尔丁·阿布都艾尼, 木拉提·热夏提*：新疆医科大学第一附属医院泌尿外科，新疆 乌鲁木齐
关键词: 膀胱癌；前列腺癌；双原发癌；Bladder Cancer； Prostate Cancer； Double Primary Cancers
摘要: 随着癌症患者生存期延长，临床上双原发癌(Double Primary Cancers, DPC)患者的日益增多，成为不可忽视的临床问题，该领域也开始变为当前研究的热点，其治疗方式并没有统一的诊疗规范，但各个研究报道的相关结论并未形成共识，本文就膀胱及前列腺双原发癌研究现状进行文献综述，以期增加对其的认识及为临床上治疗此类患者提供理论参考。
Abstract: With the extension of the survival of cancer patients, the increasing number of clinical patients with double primary cancers (DPC) has become a clinical problem that cannot be ignored. This field has also become a hotspot of current research. There is no uniform diagnosis and treatment norm for its treatment, but no consensus has been reached on relevant conclusions reported by various studies. This article reviews the research status of bladder and prostate double primary cancer in order to increase the understanding of it and provide theoretical reference for clinical treatment of this kind of patients.
文章引用：凯买尔丁·阿布都艾尼, 木拉提·热夏提. 膀胱及前列腺双原发癌的临床研究进展[J]. 临床医学进展, 2023, 13(3): 4072-4076. https://doi.org/10.12677/ACM.2023.133584

参考文献

[1] Xia C.F., Dong, X.S., Li, H., et al. (2022) Cancer Statistics in China and United States, 2022: Profiles, Trends, and De-terminants. Chinese Medical Journal, 135, 584-590. [Google Scholar] [CrossRef] 
[2] Siegel, R.L., Miller, K.D., Fuchs, H.E. and Jemal, A. (2022) Cancer Statistics, 2022. CA: A Cancer Journal for Clinicians, 72, 7-33. [Google Scholar] [CrossRef] [PubMed]
[3] Cathomas, R., Lorch, A., Bruins, H.M., et al. (2022) The 2021 Up-dated European Association of Urology Guidelines on Metastatic Urothelial Carcinoma. European Urology, 81, 95-103. [Google Scholar] [CrossRef] [PubMed]
[4] 陈双双, 马锐. 多原发癌的研究进展[J]. 癌症进展, 2019, 17(8): 883-886.
[5] Bruinsma, S.M., Bangma, C.H., Carroll, P.R., et al. (2016) Active Surveillance for Prostate Can-cer: A Narrative Review of Clinical Guidelines. Nature Reviews Urology, 13, 151-167. [Google Scholar] [CrossRef] [PubMed]
[6] Qarro, A., Ammani, A., Bazine, K., Najoui, M., Samir, J. and Alami, M. (2014) Synchronous Primary Malignancies of the Male Urogenital Tract. Canadian Urological Association Journal, 8, E353-E355. [Google Scholar] [CrossRef] [PubMed]
[7] Jing, Y., Zhang, R., Ma, P., Cai, M.-C., Zhuang, G. and Chen, H. (2018) Prevalence and Clonality of Synchronous Primary Carcinomas in the Bladder and Prostate. The Journal of Pathology, 244, 5-10. [Google Scholar] [CrossRef] [PubMed]
[8] 吴鹏飞, 郭长城, 姚旭东. 雄激素受体在膀胱癌中表达及价值——基于TCGA数据库分析[J]. 中国男科学杂志, 2018, 32(6): 38-41.
[9] Izumi, K., Taguri, M., Miyamoto, H., et al. (2014) Androgen Deprivation Therapy Prevents Bladder Cancer Recurrence. Oncotarget, 5, 12665-12674. [Google Scholar] [CrossRef] [PubMed]
[10] 娄诚, 杜智, 高英堂. 区域癌化及其临床意义[J]. 国际肿瘤学杂志, 2007, 34(10): 747-750.
[11] Hayashi, T., Fujita, K., Hayashi, Y., et al. (2020) Mutational Landscape and Environ-mental Effects in Bladder Cancer. International Journal of Molecular Sciences, 21, Article No. 6072. [Google Scholar] [CrossRef] [PubMed]
[12] Thomas, C., Giesswein, A., Hainz, M., et al. (2015) Concomitant Gleason Score ≥7 Prostate Cancer Is an Independent Prognosticator for Poor Survival in Nonmetastatic Bladder Cancer Patients Undergoing Radical Cystoprostatectomy. International Urology and Nephrology, 47, 1789-1796. [Google Scholar] [CrossRef] [PubMed]
[13] Brookman-May, S.D., Campi, R., Henríquez, J.D.S., et al. (2019) Latest Evidence on the Impact of Smoking, Sports, and Sexual Activity as Modifiable Lifestyle Risk Factors for Prostate Cancer Incidence, Recurrence, and Progression: A Systematic Review of the Literature by the European Association of Urology Section of Oncological Urology (ESOU). European Urology Focus, 5, 756-787. [Google Scholar] [CrossRef] [PubMed]
[14] Romaszko-Wojtowicz, A., Buciński, A. and Doboszyńska, A. (2018) Impact of Smoking on Multiple Primary Cancers Survival: A Retrospective Analysis. Clinical and Experimental Medi-cine, 18, 391-397. [Google Scholar] [CrossRef] [PubMed]
[15] Moschini, M., Zaffuto, E., Karakiewicz, P.I., et al. (2019) External Beam Radiotherapy Increases the Risk of Bladder Cancer When Compared with Radical Prostatectomy in Patients Af-fected by Prostate Cancer: A Population-Based Analysis. European Urology, 75, 319-328. [Google Scholar] [CrossRef] [PubMed]
[16] Shiota, M., Yokomizo, A., Takeuchi, A., et al. (2015) Secondary Bladder Cancer after Anticancer Therapy for Prostate Cancer: Reduced Comorbidity after Androgen-Deprivation Therapy. Oncotarget, 6, 14710-14719. [Google Scholar] [CrossRef] [PubMed]
[17] 孙俊杰, 李双庆. 多原发癌病因及发病机制的探索[J]. 中国全科医学, 2017, 20(9): 1136-1141.
[18] Lopez-Beltran, A., Cheng, L., Montorsi, F., et al. (2017) Concomitant Bladder Cancer and Prostate Cancer: Challenges and Controversies. Nature Reviews Urology, 14, 620-629. [Google Scholar] [CrossRef] [PubMed]
[19] 赵国栋, 刘士军, 胡浩. 前列腺偶发癌的临床分期及治疗方案与预后的相关性研究[J]. 临床和实验医学杂志, 2014, 13(12): 1014-1016.
[20] Malte, R., Kluth, L.A., Kaushik, D., et al. (2017) Frequency and Prognostic Significance of Incidental Prostate Cancer at Radical Cystectomy: Results from an International Retrospective Study. European Journal of Surgical Oncology, 43, 2193-2199. [Google Scholar] [CrossRef] [PubMed]
[21] Pignot, G., Salomon, L., Neuzillet, Y., et al. (2014) Clinicopatho-logical Characteristics of Incidental Prostate Cancer Discovered from Radical Cystoprostatectomy Specimen: A Multi-center French Study. Annals of Surgical Oncology, 21, 684-690. [Google Scholar] [CrossRef] [PubMed]
[22] Jønck, S., Helgstrand, J.T., Røder, M.A., et al. (2018) The Prog-nostic Impact of Incidental Prostate Cancer Following Radical Cystoprostatectomy: A Nationwide Analysis. Scandinavi-an Journal of Urology, 52, 358-363. [Google Scholar] [CrossRef] [PubMed]
[23] Fahmy, O., Khairul-Asri, M.G., Schubert, T., et al. (2017) Clinicopathological Features and Prognostic Value of Incidental Prostatic Adenocarcinoma in Radical Cystoprostatectomy Specimens: A Systematic Review and Meta-Analysis of 13,140 Patients. Journal of Urology, 197, 385-390. [Google Scholar] [CrossRef] [PubMed]
[24] Buse, S., et al. (2013) Characterization and Risk Stratification of Prostate Cancer in Patients Undergoing Radical Cystoprostatectomy. International Journal of Urology, 20, 866-871. [Google Scholar] [CrossRef] [PubMed]
[25] Kong, Y., Li, J., Lin, H., Liang, X. and Zhou, X. (2022) Landscapes of Synchronous Multiple Primary Cancers Detected by Next-Generation Sequencing. FEBS Open Bio, 12, 1996-2005. [Google Scholar] [CrossRef] [PubMed]
[26] Cavazos, T.B., Kachuri, L., Graff, R.E., et al. (2022) Assessment of Genetic Susceptibility to Multiple Primary Cancers through Whole-Exome Sequencing in Two Large Multi-Ancestry Studies. BMC Medicine, 20, Article No. 332. [Google Scholar] [CrossRef] [PubMed]

为你推荐