小气道功能障碍与哮喘控制
Small Airway Dysfunction and Asthma Control
DOI: 10.12677/ACM.2023.133593, PDF,   
作者: 易良琴, 罗征秀:重庆医科大学附属儿童医院呼吸科,重庆;国家儿童健康与疾病临床医学研究中心,重庆;儿童发育疾病研究教育部重点实验室,重庆;儿科学重庆市重点实验室,重庆
关键词: 哮喘控制小气道功能障碍Asthma Control Small Airway Dysfunction
摘要: 哮喘是常见的慢性气道炎症性疾病,炎症可累及整个气管–支气管树,近年来,小气道被认为是炎症累及和气流阻塞的主要部位,小气道功能障碍是持续性哮喘的特征,与疾病恶化和控制不良相关,但目前指南尚缺少小气道管理相关内容。本文就小气道功能障碍与哮喘控制关系做一综述,以期提升对小气道功能障碍在哮喘控制中作用的认知水平,为哮喘指南的完善提供支持性证据。
Abstract: Asthma is a common chronic airway disease. Inflammation in asthma can involve the entire tra-chea-bronchial tree. Recent years, small airways have been accepted to be the main site of inflam-mation and major reason of airflow obstruction. And small airway dysfunction is confirmed as a characteristic of persistent asthma, which is related to exacerbation and control. However, in asth-ma guidelines, little information is stressing the role of small airway. In this review article, we fo-cused on the relationship between small airway dysfunction and asthma control, pointed out the in-fluence of small airway dysfunction in poor asthma control and stressed the importance of its man-agement, in order to provide supporting evidence for asthma guideline.
文章引用:易良琴, 罗征秀. 小气道功能障碍与哮喘控制[J]. 临床医学进展, 2023, 13(3): 4129-4135. https://doi.org/10.12677/ACM.2023.133593

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