电化学生物传感器在检测新型冠状病毒中的应用
Application of Electrochemical Biosensor in Detection of SARS-CoV-2
DOI: 10.12677/OJNS.2023.112028, PDF,   
作者: 邹燕娇：武汉工程大学化学与环境工程学院，湖北 武汉
关键词: 电化学传感器；生物识别；新型冠状病毒；Electrochemical Sensor； Biometrics； Novel Coronavirus
摘要: 自2019年12月新型冠状病毒引发的肺炎爆发以来，对全世界的公共卫生都造成了巨大的危害，现存的检测技术对于新型冠状病毒的检测仍具有一定的局限性，目前常见的三种分析检测方法分别是胸部CT扫描结合临床症状、基于RT-qPCR的核糖核酸检测以及基于横向流动免疫层析试纸(LFICS)、全自动化学发光试验和酶联免疫吸附试验(ELISA)的抗体检测。这三种检测方法多半需要结合使用，且存在检测结果假阴性的现象。目前，需要开发一种更加灵敏、结果更加准确的检测手段，电化学生物传感器作为一种将电化学方法与生物特异性识别相结合的方法，在检测SARS-CoV-2上具有一定的应用前景，本文综述了电化学生物传感器在检测SARS-CoV-2上的最新研究进展。
Abstract: Since the outbreak of pneumonia caused by SARS-CoV-2 in December 2019, it has caused great harm to public health all over the world. The existing detection techniques for emerging coronavirus still have certain limitations. At present, three common analytical methods are chest CT scan combined with clinical symptoms, RT-qPCR-based ribonucleic acid detection, and antibody detection based on transverse flow immunotomography (LFICS), automatic chemiluminescence test and enzyme linked immunosorbent assay (ELISA). Most of the three test methods need to be used in combination, and there is a phenomenon of false positive results. At present, it is necessary to develop a more sensitive detection method with more accurate results. Electrochemical biosensor, as a method combining electrochemical method with biological specific recognition, has a certain application prospect in the detection of SARS-CoV-2. In this paper, the latest research progress of electrochemical biosensor in the detection of SARS-CoV-2 is reviewed.
文章引用：邹燕娇. 电化学生物传感器在检测新型冠状病毒中的应用[J]. 自然科学, 2023, 11(2): 236-242. https://doi.org/10.12677/OJNS.2023.112028

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