中药联合胰岛素泵强化治疗2型糖尿病的研究进展

Research Progress of Intensive Treatment for Type 2 Diabetes with Traditional Chinese Medicine Combined with Insulin Pump

摘要: 随着糖尿病患病率的不断增加，人们对于胰岛素泵强化治疗2型糖尿病(T2DM)已经达成相关共识。胰岛素泵强化治疗可以短期内稳定血糖水平，改善胰岛β细胞功能，延缓相关并发症的发生、发展，降低心血管事件的发生率，同时也带来了低血糖、体重增加等相关因素的风险；然而中药在很大程度上弥补了胰岛素泵强化治疗的缺点。中药联合胰岛素泵强化治疗在高效平稳降糖的同时，可更好地修复β细胞功能，进一步改善胰岛素抵抗，减少胰岛素的使用量，改善患者的临床症状，调节脂代谢，防止体重增加，减少低血糖反应，延缓并发症的发生与发展，改善糖尿病患者的远期预后。本文就近五年关于中药联合胰岛素泵强化治疗2型糖尿病的研究进展进行探讨。

Abstract: With the increasing prevalence of diabetes mellitus, there has been a consensus on intensive insu-lin pump therapy for type 2 diabetes mellitus (T2DM). Intensive treatment with insulin pump can stabilize blood glucose levels in the short term, improve the function of pancreatic beta cells, delay the occurrence and development of related complications, and reduce the incidence of cardiovascu-lar events, but also brings the risk of hypoglycemia, weight gain and other related factors. Chinese medicine makes up for the shortcomings of intensive insulin pump therapy to a large extent. Chi-nese medicine combined with insulin pump intensive therapy can better repair β cell function, fur-ther improve insulin resistance, reduce the use of insulin, improve patients’ clinical symptoms, reg-ulate lipid metabolism, prevent weight gain, reduce hypoglycemia reaction, delay the occurrence and development of complications, and improve the long-term prognosis of diabetes patients. In this paper, the research progress of intensive treatment of type 2 diabetes with traditional Chinese medicine combined with insulin pump in recent five years was discussed.