Lennox-Gastaut综合征的研究进展
Advances in Research on Lennox-Gastaut Syndrome
DOI: 10.12677/ACM.2023.133701, PDF,   
作者: 钟 莉, 曹 洁*：重庆医科大学附属儿童医院全科医学科，重庆；儿童发育疾病研究教育部重点实验室，重庆；国家儿童健康与疾病临床医学研究中心，重庆；儿童发育重大疾病国家国际科技合作基地，重庆；儿科学重庆市重点实验室，重庆
关键词: Lenox-Gastaut综合征；癫痫；抗癫痫药物；Lenox-Gastaut Syndrome； Epilepsy； Antiepileptic Drug
摘要: Lenox-Gastaut综合征(LGS)是一种儿童期发病，以多种癫痫发作类型、异常脑电图及认知和/或行为障碍为主要特征的癫痫性脑病。大多数LGS患儿为难治性癫痫，常伴有智力障碍及发育迟缓，严重影响患儿的生活质量。在此从病因、发病机制、临床特点、脑电图特征、诊断、治疗及预后等方面进行综述，以期为LGS患儿的诊疗提供思路与参考。
Abstract: Lenox-Gastaut syndrome (LGS) is a childhood epileptic encephalopathy characterized by multiple seizure types, abnormal electroencephalography, and cognitive and/or behavioral disorders. Most children with LGS have intractable epilepsy, often accompanied by intellectual impairment and de-velopmental delay, which seriously affect the quality of life of the children. In this paper, etiology, pathogenesis, clinical features, EEG characteristics, diagnosis, treatment and prognosis are re-viewed, in order to provide ideas and reference for the diagnosis and treatment of children with LGS.
文章引用：钟莉, 曹洁. Lennox-Gastaut综合征的研究进展[J]. 临床医学进展, 2023, 13(3): 4912-4918. https://doi.org/10.12677/ACM.2023.133701

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