新生儿坏死性小肠结肠炎肠内营养策略
Enteral Nutrition Strategy for Neonatal Necrotizing Enterocolitis
DOI: 10.12677/ACM.2023.133707, PDF,   
作者: 杜 鹏, 康 权：重庆医科大学附属儿童医院普外创伤外科，重庆；国家儿童健康与疾病临床医学研究中心，重庆；儿童发育疾病研究教育部重点实验室，重庆
关键词: 新生儿坏死性小肠结肠炎；肠内营养；喂养；营养；Neonatal Necrotizing Enterocolitis； Enteral Nutrition； Feeding； Nutrition
摘要: 新生儿坏死性小肠结肠炎(neonatal necrotizing enterocolitis, NEC)常见于全球新生儿重症监护室(neonatal intensive care unit, NICU)，尤其多发生在那些早产或低出生体重的新生儿，该病以肠道继发坏死病变为特点，是一种新生儿毁灭性疾病，如不早期发现并及时干预，生存机会极低，即使存活临床医生也仍需面临与之相关的严重且复杂的后遗症问题，且该病还有一定的复发风险。虽然针对病因治疗该病还无从下手，但就目前众多NEC预防与治疗管理策略中可以知道合理的喂养指导可以降低NEC发生率，并安全尽快地为早产儿或NEC患儿建立足够的肠内营养支持。围绕NEC营养方面的知识仍存在很大差距，需要更多的研究来确定预防NEC或NEC后的最佳喂养方法，本综述旨在讨论营养和喂养方式在坏死性小肠结肠炎(NEC)中的作用，为NEC相关营养管理提供一些参考依据。
Abstract: Neonatal necrotizing enterocolitis (NEC) is common in neonatal intensive care unit (NICU), especial-ly in premature or low birth weight neonates. NEC is characterized by intestinal necrotic lesions. It is a devastating neonatal disease. If it is not detected early and intervened in time, the survival chance is extremely low. Even if it survives, clinicians still have to face serious and complex seque-lae related to it, and the disease still has a certain risk of recurrence. Although there is no way to treat the disease according to the etiology, we can know that reasonable feeding guidance can re-duce the incidence of NEC and establish enough enteral nutrition support for premature infants or children with NEC safely and as soon as possible. There is still a big gap in the knowledge of NEC nu-trition. More research is needed to determine the best feeding method for preventing NEC or after NEC. The purpose of this review is to discuss the role of nutrition and feeding methods in necrotizing enterocolitis (NEC) and provide some reference for NEC-related nutrition management.
文章引用：杜鹏, 康权. 新生儿坏死性小肠结肠炎肠内营养策略[J]. 临床医学进展, 2023, 13(3): 4958-4964. https://doi.org/10.12677/ACM.2023.133707

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