|
[1]
|
Feliciangeli, S., et al. (2007) Does Sumoylation Control K2P1/TWIK1 Background K+ Channels? Cell, 130, 563-569. [Google Scholar] [CrossRef] [PubMed]
|
|
[2]
|
Bichet, D., Blin, S., Feliciangeli, S., Chatelain, F.C., Bobak, N. and Lesage, F. (2015) Silent but not Dumb: How Cellular Trafficking and Pore Gating Modulate Expression of TWIK1 and THIK2. Pflügers Archiv-European Journal of Physiology, 467, 1121-1131. [Google Scholar] [CrossRef] [PubMed]
|
|
[3]
|
Renigunta, V., Zou, X., Kling, S., Schlichthörl, G. and Daut, J. (2014) Breaking the Silence: Functional Expression of the Two-Pore-Domain Potassium Channel THIK-2. Pflügers Archiv-European Journal of Physiology, 466, 1735-1745. [Google Scholar] [CrossRef] [PubMed]
|
|
[4]
|
Lesage, F., Guillemare, E., Fink, M., Duprat, F., Lazdunski, M., Romey, G. and Barhanin, J. (1996) TWIK-1, a Ubiquitous Human Weakly Inward Rectifying K+ Channel with a Novel Structure. The EMBO Journal, 15, 1004-1011. [Google Scholar] [CrossRef] [PubMed]
|
|
[5]
|
Lloyd, E.E., Marrelli, S.P., Namiranian, K. and Bryan, R.M. (2009) Characterization of TWIK-2, a Two-Pore Domain K+ Channel, Cloned from the Rat Middle Cerebral Artery. Experimental Biology and Medicine, 234, 1493-1502. [Google Scholar] [CrossRef]
|
|
[6]
|
Medhurst, A.D., et al. (2001) Distribution Analysis of Human Two Pore Domain Potassium Channels in Tissues of the Central Nervous System and Periphery. Molecular Brain Research, 86, 101-114. [Google Scholar] [CrossRef]
|
|
[7]
|
Bechard, E., et al. (2022) TREK-1 in the Heart: Potential Physiological and Pathophysiological Roles. Frontiers in Physiology, 13, Article 1095102. [Google Scholar] [CrossRef] [PubMed]
|
|
[8]
|
Lesage, F., Terrenoire, C., Romey, G. and Lazdunski, M. (2000) Human TREK2, a 2P Domain Mechano-Sensitive K+ Channel with Multiple Regulations by Polyunsaturated Fatty Acids, Lysophospholipids, and Gs, Gi and Gq Protein-Coupled Receptors. Journal of Biological Chemistry, 275, 28398-28405. [Google Scholar] [CrossRef]
|
|
[9]
|
Maingret, F., Fosset, M., Lesage, F., Lazdunski, M. and Honoré, E. (1999) TRAAK Is a Mammalian Neuronal Mechano-Gated K+ Channel. Journal of Biological Chemistry, 274, 1381-1387. [Google Scholar] [CrossRef] [PubMed]
|
|
[10]
|
Bandulik, S., Penton, D., Barhanin, J. and Warth, R. (2010) TASK1 and TASK3 Potassium Channels: Determinants of Aldosterone Secretion and Adrenocortical Zonation. Hormone and Metabolic Research, 42, 450-457. [Google Scholar] [CrossRef] [PubMed]
|
|
[11]
|
Bayliss, D.A., Barhanin, J., Gestreau, C. and Guyenet, P.G. (2015) The Role of pH-Sensitive TASK Channels in Central Respiratory Chemoreception. Pflügers Archiv-European Journal of Physiology, 467, 917-929. [Google Scholar] [CrossRef] [PubMed]
|
|
[12]
|
Ashmole, I., Goodwin, P.A. and Stanfield, P.R. (2001) TASK-5, a Novel Member of the Tandem Pore K+ Channel Family. Pflügers Archiv, 442, 828-833. [Google Scholar] [CrossRef] [PubMed]
|
|
[13]
|
Theilig, F., et al. (2008) Cellular Localization of THIK-1 (K2P13.1) and THIK-2 (K2P12.1) K+ Channels in the Mammalian Kidney. Cellular Physiology and Biochemistry, 21, 63-74. [Google Scholar] [CrossRef] [PubMed]
|
|
[14]
|
Duprat, F., Girard, C., Jarretou, G. and Lazdunski, M. (2005) Pancreatic Two P Domain K+ Channels TALK-1 and TALK-2 Are Activated by Nitric Oxide and Reactive Oxygen Species. The Journal of Physiology, 562, 235-244. [Google Scholar] [CrossRef] [PubMed]
|
|
[15]
|
Sun, X.Y., Li, Y.Z., Lan, H., Jiang, T., Wan, X.Y. and Cheng, Y. (2023) Identification of KCNK1 as a Potential Prognostic Biomarker and Therapeutic Target of Breast Cancer. Pathology-Research and Practice, 241, Article ID: 154286. [Google Scholar] [CrossRef] [PubMed]
|
|
[16]
|
Christensen, A.H., et al. (2016) The Two-Pore Domain Potassium Channel, TWIK-1, Has a Role in the Regulation of Heart Rate and Atrial Size. JMCC: Journal of Molecular and Cellular Cardiology, 97, 24-35. [Google Scholar] [CrossRef] [PubMed]
|
|
[17]
|
Mhatre, A.N., et al. (2004) Genomic Structure, Cochlear Expression, and Mutation Screening of KCNK6, a Candidate Gene for DFNA4. Journal of Neuroscience Research, 75, 25-31. [Google Scholar] [CrossRef] [PubMed]
|
|
[18]
|
Kitagawa, M.G., Reynolds, J.O., Durgan, D., Rodney, G., Karmouty-Quintana, H., Bryan, R. and Pandit, L.M. (2019) Twik-2-/- Mouse Demonstrates Pulmonary Vascular Heterogeneity in Intracellular Pathways for Vasocontractility. Physiological Reports, 7, e13950. [Google Scholar] [CrossRef] [PubMed]
|
|
[19]
|
Pathan, A.R. and Rusch, N.J. (2011) Two-Pore Domain K⁺ Channels: Evidence for TWIK-2 in Blood Pressure Regulation. Hypertension, 58, 539-541. [Google Scholar] [CrossRef]
|
|
[20]
|
Wu, X.Y., et al. (2022) ML365 Inhibits TWIK2 Channel to Block ATP-Induced NLRP3 Inflammasome. Acta Pharmacologica Sinica, 43, 992-1000. [Google Scholar] [CrossRef] [PubMed]
|
|
[21]
|
Mukherjee, S. and Sikdar, S.K. (2021) Intracellular Activation of Full-Length Human TREK-1 Channel by Hypoxia, High Lactate, and Low pH Denotes Polymodal Integration by Ischemic Factors. Pflügers Archiv-European Journal of Physiology, 473, 167-183. [Google Scholar] [CrossRef] [PubMed]
|
|
[22]
|
Arazi, E., Blecher, G. and Zilberberg, N. (2020) A Regulatory Domain in the K2P2.1 (TREK-1) Carboxyl-Terminal Allows for Channel Activation by Monoterpenes. Molecular and Cellular Neuroscience, 105, Article ID: 103496. [Google Scholar] [CrossRef] [PubMed]
|
|
[23]
|
Kondo, R., Deguchi, A., Kawata, N., Suzuki, Y. and Yamamura, H. (2022) Involvement of TREK1 Channels in the Proliferation of Human Hepatic Stellate LX-2 Cells. Journal of Pharmacological Sciences, 148, 286-294. [Google Scholar] [CrossRef] [PubMed]
|
|
[24]
|
Sauter, D.R., Sørensen, C.E., Rapedius, M., Brüggemann, A. and Novak, I. (2016) pH-Sensitive K+ Channel TREK-1 Is a Novel Target in Pancreatic Cancer. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1862, 1994-2003. [Google Scholar] [CrossRef] [PubMed]
|
|
[25]
|
Busserolles, J., et al. (2020) TREK1 Channel Activation as a New Analgesic Strategy Devoid of Opioid Adverse Effects. British Journal of Pharmacology, 177, 4782-4795. [Google Scholar] [CrossRef] [PubMed]
|
|
[26]
|
Huang, D. and Yu, B. (2008) Recent Advance and Possible Future in TREK-2: A Two-Pore Potassium Channel May involved in the Process of NPP, Brain Ischemia and Memory Impairment. Medical Hypotheses, 70, 618-624. [Google Scholar] [CrossRef] [PubMed]
|
|
[27]
|
Messina, D.N., Peralta, E.D. and Acosta, C.G. (2022) Glial-Derived Neurotrophic Factor Regulates the Expression of TREK2 in Rat Primary Sensory Neurons Leading to Attenuation of Axotomy-Induced Neuropathic Pain. Experimental Neurology, 357, Article ID: 114190. [Google Scholar] [CrossRef] [PubMed]
|
|
[28]
|
Acosta, C., et al. (2014) TREK2 Expressed Selectively in IB4-Binding C-Fiber Nociceptors Hyperpolarizes Their Membrane Potentials and Limits Spontaneous Pain. Journal of Neuroscience, 34, 1494-509. [Google Scholar] [CrossRef]
|
|
[29]
|
Park, K.S., et al. (2013) The TREK2 Channel Is Involved in the Proliferation of 253J Cell, a Human Bladder Carcinoma Cell. The Korean Journal of Physiology & Pharmacology, 17, 511-516. [Google Scholar] [CrossRef] [PubMed]
|
|
[30]
|
Rietmeijer, R.A., Sorum, B., Li, B.B. and Brohawn, S.G. (2021) Physical Basis for Distinct Basal and Mechanically Gated Activity of the Human K+ Channel TRAAK. Neuron, 109, 2902-2913. [Google Scholar] [CrossRef] [PubMed]
|
|
[31]
|
Schrecke, S., et al. (2021) Selective Regulation of Human TRAAK Channels by Biologically Active Phospholipids. Nature Chemical Biology, 17, 89-95. [Google Scholar] [CrossRef] [PubMed]
|
|
[32]
|
Fan, X., Lu, Y,Z., Du, G.Z. and Liu, J. (2022) Advances in the Understanding of Two-Pore Domain TASK Potassium Channels and Their Potential as Therapeutic Targets. Molecules, 27, Article 8296. [Google Scholar] [CrossRef] [PubMed]
|
|
[33]
|
Sörmann, J., et al. (2022) Gain-of-Function Mutations in KCNK3 Cause a Developmental Disorder with Sleep Apnea. Nature Genetics, 54, 1534-1543. [Google Scholar] [CrossRef] [PubMed]
|
|
[34]
|
Yeo, Y., et al. (2022) Crosstalk between BMP Signaling and KCNK3 in Phenotypic Switching of Pulmonary Vascular Smooth Muscle Cells. BMB Reports, 55, 565-570. [Google Scholar] [CrossRef]
|
|
[35]
|
Wiedmann, F., et al. (2022) MicroRNAs Regulate TASK-1 and Are Linked to Myocardial Dilatation in Atrial Fibrillation. Journal of the American Heart Association, 11, e023472. [Google Scholar] [CrossRef]
|
|
[36]
|
Bandulik, S., Tauber, P., Lalli, E., Barhanin, J. and Warth, R. (2015) Two-Pore Domain Potassium Channels in the Adrenal Cortex. Pflügers Archiv-European Journal of Physiology, 467, 1027-1042. [Google Scholar] [CrossRef] [PubMed]
|
|
[37]
|
Leithner, K., et al. (2016) TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers. PLOS ONE, 11, e0157453. [Google Scholar] [CrossRef] [PubMed]
|
|
[38]
|
Bittner, S., et al. (2012) The TASK1 Channel Inhibitor A293 Shows Efficacy in a Mouse Model of Multiple Sclerosis. Experimental Neurology, 238, 149-155. [Google Scholar] [CrossRef] [PubMed]
|
|
[39]
|
Lenzini, L., Prisco, S., Gallina, M., Kuppusamy, M. and Rossi, G.P. (2018) Mutations of the Twik-Related Acid-Sensitive K+ Channel 2 Promoter in Human Primary Aldosteronism. Endocrinology, 159, 1352-1359. [Google Scholar] [CrossRef] [PubMed]
|
|
[40]
|
Reed, A.P., Bucci, G., Abd-Wahab, F. and Tucker, S.J. (2016) Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy. PLOS ONE, 11, e0156456. [Google Scholar] [CrossRef] [PubMed]
|
|
[41]
|
Schulte-Mecklenbeck, A., et al. (2015) The Two-Pore Domain K2P Channel TASK2 Drives Human NK-Cell Proliferation and Cytolytic Function. European Journal of Immunology, 45, 2602-2614. [Google Scholar] [CrossRef] [PubMed]
|
|
[42]
|
Saito, M., Tanaka, C., Toyoda, H. and Kang, Y. (2022) Subcellular Localization of Homomeric TASK3 Channels and Its Presumed Functional Significances in Trigeminal Motoneurons. International Journal of Molecular Sciences, 24, Article 344. [Google Scholar] [CrossRef] [PubMed]
|
|
[43]
|
Chu, L.H., et al. (2022) Epigenomic Analysis Reveals the KCNK9 Potassium Channel as a Potential Therapeutic Target for Adenomyosis. International Journal of Molecular Sciences, 23, Article 5973. [Google Scholar] [CrossRef] [PubMed]
|
|
[44]
|
Cikutović-Molina, R., Herrada, A.A., González, W., Brown, N. and Zúñiga, L. (2019) TASK-3 Gene Knockdown Dampens Invasion and Migration and Promotes Apoptosis in KATO III and MKN-45 Human Gastric Adenocarcinoma Cell Lines. International Journal of Molecular Sciences, 20, Article 6077. [Google Scholar] [CrossRef] [PubMed]
|
|
[45]
|
Innamaa, A., et al. (2013) Expression and Prognostic Significance of the Oncogenic K2P Potassium Channel KCNK9 (TASK-3) in Ovarian Carcinoma. Anticancer Research, 33, 1401-1408.
|
|
[46]
|
Zúñiga, R., Valenzuela, C., Concha, G., Brown, N. and Zúñiga, L. (2018) TASK-3 Downregulation Triggers Cellular Senescence and Growth Inhibition in Breast Cancer Cell Lines. International Journal of Molecular Sciences, 19, Article 1033. [Google Scholar] [CrossRef] [PubMed]
|
|
[47]
|
Nagy, D., et al. (2014) Silencing the KCNK9 Potassium Channel (TASK-3) Gene Disturbs Mitochondrial Function, Causes Mitochondrial Depolarization and Induces Apoptosis of Human Melanoma Cells. Archives of Dermatological Research, 306, 885-902. [Google Scholar] [CrossRef] [PubMed]
|
|
[48]
|
Cousin, M.A., et al. (2022) Gain and Loss of TASK3 Channel Function and Its Regulation by Novel Variation Cause KCNK9 Imprinting Syndrome. Genome Medicine, 14, Article No. 62. [Google Scholar] [CrossRef] [PubMed]
|
|
[49]
|
Friedrich, C., et al. (2014) Gain-of-Function Mutation in TASK-4 Channels and Severe Cardiac Conduction Disorder. EMBO Molecular Medicine, 6, 937-951. [Google Scholar] [CrossRef] [PubMed]
|
|
[50]
|
Karschin, C., et al. (2001) Expression Pattern in Brain of TASK-1, TASK-3, and a Tandem Pore Domain K+ Channel Subunit, TASK-5, Associated with the Central Auditory Nervous System. Molecular and Cellular Neuroscience, 18, 632-648. [Google Scholar] [CrossRef] [PubMed]
|
|
[51]
|
Haskins, W., Benitez, S., Mercado, J.M. and Acosta, C.G. (2017) Cutaneous Inflammation Regulates THIK1 Expression in Small C-Like Nociceptor Dorsal Root Ganglion Neurons. Molecular and Cellular Neuroscience, 83, 13-26. [Google Scholar] [CrossRef] [PubMed]
|
|
[52]
|
Drinkall, S., et al. (2022) The Two Pore Potassium Channel THIK-1 Regulates NLRP3 Inflammasome Activation. Glia, 70, 1301-1316. [Google Scholar] [CrossRef] [PubMed]
|
|
[53]
|
Girard, C., et al. (2001) Genomic and Functional Characteristics of Novel Human Pancreatic 2P Domain K+ Channels. Biochemical and Biophysical Research Communications, 282, 249-256. [Google Scholar] [CrossRef] [PubMed]
|
|
[54]
|
Chatelain, F.C., et al. (2013) Silencing of the Tandem Pore Domain Halothane-Inhibited K+ Channel 2 (THIK2) Relies on Combined Intracellular Retention and Low Intrinsic Activity at the Plasma Membrane. Journal of Biological Chemistrym, 288, 35081-35092. [Google Scholar] [CrossRef]
|
|
[55]
|
Dickerson, M.T., Vierra, N.C., Milian, S.C., Dadi, P.K. and Jacobson, D.A. (2017) Osteopontin Activates the Diabetes-Associated Potassium Channel TALK-1 in Pancreatic β-Cells. PLOS ONE, 12, e0175069. [Google Scholar] [CrossRef] [PubMed]
|
|
[56]
|
Vierra, N.C., et al. (2015) Type 2 Diabetes-Associated K+ Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis. Diabetes, 64, 3818-3828. [Google Scholar] [CrossRef] [PubMed]
|
|
[57]
|
Vierra, N.C., et al. (2017) TALK-1 Channels Control β Cell Endoplasmic Reticulum Ca2+ Homeostasis. Science Signaling, 10, aan2883. [Google Scholar] [CrossRef] [PubMed]
|
|
[58]
|
Imbrici, P., et al. (2020) Altered Functional Properties of a Missense Variant in the TRESK K+ Channel (KCNK18) Associated with Migraine and Intellectual Disability. Pflügers Archiv-European Journal of Physiology, 472, 923-930. [Google Scholar] [CrossRef] [PubMed]
|
|
[59]
|
Pergel, E., Lengyel, M., Enyedi, P. and Czirják, G. (2019) TRESK (K2P18.1) Background Potassium Channel Is Activated by Novel-Type Protein Kinase C via Dephosphorylation. Molecular Pharmacology, 95, 661-672. [Google Scholar] [CrossRef] [PubMed]
|
|
[60]
|
Schreiber, J.A., Düfer, M. and Seebohm, G. (2022) The Special One: Architecture, Physiology and Pharmacology of the TRESK Channel. Cellular Physiology & Biochemistry, 56, 663-684. [Google Scholar] [CrossRef] [PubMed]
|
|
[61]
|
Andres-Bilbe, A., et al. (2020) The Background K+ Channel TRESK in Sensory Physiology and Pain. International Journal of Molecular Sciences, 21, Article 5206. [Google Scholar] [CrossRef] [PubMed]
|