MHT治疗绝经综合征的现况概括

Current Status of MHT Treatment for Menopausal Syndrome

摘要: 目的：探讨如何更好地运用绝经激素治疗(Menopausal hormone therapy, MHT)治疗绝经综合征。方法：广泛查阅近5年文献，汇总了目前国内外对绝经综合征及MHT的认识。结果：MHT有雌激素，孕激素，复方雌激素 + 孕激素，给药途径包括口服及透皮途径给药等多种方式，应针对患者症状选择个体治疗。结论：MHT对绝经期女性利远远大于弊，但大对数女性对MHT认识不足，过于恐惧其风险而对于其益处却熟视无睹，这显然需要医生及医学生做出更大努力来指导广大妇女了解更年期的病理生理及激素治疗的作用，希望在与健康生活方式的协同作用下，MHT可以改善女性更年期的症状和体征，促进健康长寿。

Abstract: Objective: To explore how to better use postmenopausal hormone therapy (Menopausal-hormonetherapy, MHT) treatment of menopausal syndrome. Methods: The literature of the past 5 years was reviewed extensively, and the understanding of menopausal syndrome and MHT at home and abroad was summarized. Results: MHT has estrogen, progesterone and compound estrogen + progesterone. The administration routes include oral administration and transdermal administra-tion. Individual treatment should be selected according to patients’ symptoms. Conclusion: The ad-vantages of MHT in menopausal women far outweigh the disadvantages, but most women do not know enough about MHT. They are too afraid of its risks and turn a blind eye to its benefits. It is ob-viously necessary for doctors and medical students to make greater efforts to guide women to un-derstand the pathophysiology of menopause and the role of hormone therapy. MHT can improve the symptoms and signs of female menopause and promote healthy longevity.