儿童流感嗜血杆菌流行病学及感染变化
Epidemiology and Infection Changes of Haemophilus Influenzae in Children
DOI: 10.12677/ACM.2023.134766, PDF,   
作者: 郑文婷, 李渠北*：重庆医科大学附属儿童医院呼吸中心，儿科学重庆市重点实验室，儿童发育疾病研究教育部重点实验室，国家儿童健康与疾病临床医学研究中心，重庆
关键词: 儿童；流感嗜血杆菌；流行病学；疫苗接种；综述；Children； Haemophilus Influenzae； Epidemiology； Vaccination； Review
摘要: 流感嗜血杆菌是一种儿童感染常见病原菌，在开展疫苗接种之前，b型流感嗜血杆菌(Hib)是脑膜炎、儿童肺炎的重要病原体，随着Hib疫苗在各地区覆盖率的增高，流感嗜血杆菌的流行病学已经发生了变化，以无荚膜不可分型流感嗜血杆菌(NTHi)为主，并且由于流感嗜血杆菌的抗生素耐药性逐步增加，对儿童仍是较重疾病负担。本文对儿童流感嗜血杆菌的相关研究进行综述，总结其流行病学、感染现状及治疗的进展。
Abstract: Haemophilus influenzae (Hi) is a common pathogen of infection in children. Before vaccination, Haemophilus influenzae, especially Haemophilus influenzae type b (Hib), was an important cause of bacterial meningitis and pneumonia in children. With the increase of Hib vaccine coverage in vari-ous regions, the epidemiology of Haemophilus influenzae has changed, and now the nontypeable H. influenzae (NTHi) becomes the main strain. Additionally, due to the increasing of antibiotic re-sistance, H. influenzae is still a heavy disease burden for children. This article will review the epi-demiology of Haemophilus influenza, current infection status and treatment of H. influenzae in chil-dren.
文章引用：郑文婷, 李渠北. 儿童流感嗜血杆菌流行病学及感染变化[J]. 临床医学进展, 2023, 13(4): 5406-5412. https://doi.org/10.12677/ACM.2023.134766

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