昼夜节律与肾脏
Circadian Rhythms and the Kidney
DOI: 10.12677/ACM.2023.134810, PDF,   
作者: 冉景阳：重庆医科大学附属第二医院肾内科，重庆
关键词: 昼夜节律；肾脏；生物钟；昼夜节律紊乱；肾脏疾病；Circadian Rhythm； Kidney； Biological Clock； Circadian Rhythm Disorder； Kidney Disease
摘要: 作为人类健康和新陈代谢等各个方面的重要调节器，昼夜节律系统逐渐受到人们的重视，越来越多的研究开始关注昼夜节律改变对于人类健康的影响。而肾脏作为昼夜节律最明显的器官之一，其多个肾脏生理过程表现出昼夜节律，包括肾小球滤过率(GFR)、肾血浆流量(RPF)、水和电解质的排泄、激素分泌、血压调节等，而近年来多项研究显示，昼夜节律的改变可能会导致肾脏疾病的发生发展。本文就肾脏的昼夜节律特点以及昼夜节律对肾脏疾病的影响进行综述。
Abstract: The circadian system, as a major regulator of almost every aspect of human health and metabolism, has gradually attracted people’s attention. More and more researchers have begun to pay attention to the impact of circadian rhythm changes on human health. The kidney is one of the organs with the most obvious circadian rhythm, and several renal physiological processes exhibit circadian rhythms, including glomerular filtration rate (GFR), renal plasma flow (RPF), water and electrolyte excretion, hormone secretion, and blood pressure regulation. And several studies in recent years have shown that changes in circadian rhythms may contribute to the development of kidney dis-ease. This article provides a review of the circadian characteristics of the kidney and the impact of circadian rhythms on kidney disease.
文章引用：冉景阳. 昼夜节律与肾脏[J]. 临床医学进展, 2023, 13(4): 5740-5745. https://doi.org/10.12677/ACM.2023.134810

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