艾司氯胺酮在围术期麻醉应用的研究进展
Research Progress in Perioperative Anesthesia Application of Esketamine
DOI: 10.12677/ACM.2023.134874, PDF,   
作者: 徐 锐, 李晓霞*:重庆医科大学附属第二医院麻醉科,重庆
关键词: 艾司氯胺酮围术期麻醉镇静镇痛Esketamine Perioperative Anesthesia Sedation Analgesic
摘要: 氯胺酮作为一种传统的麻醉药物已经在临床使用多年,而艾司氯胺酮作为一种新型麻醉药物目前在临床麻醉中应用仍然较少。相比传统的氯胺酮,艾司氯胺酮具有更强的镇痛和镇静效力,且理论上其潜在的副作用发生率更低。本文拟阐述艾司氯胺酮应用于临床麻醉、镇静和镇痛相关的药理特性和作用机制,综述艾司氯胺酮在围术期临床应用中在麻醉、镇静和镇痛治疗等方面的相关研究进展,为艾司氯胺酮在围术期应用范围及安全合理的使用方法提供参考。
Abstract: Ketamine has been used in China for years as a traditional narcotic, but esketamine is less used in clinical anesthesia in China as a new one. Compared with ketamine, esketamine has a stronger an-algesic and sedative effect, and has a theoretically lower incidence of side effects. This review de-scribes the pharmacological characteristics and mechanism of action of esketamine in perioperative anesthesia, and introduces the relevant research progress of esketamine in perioperative anesthesia, including anesthesia, sedation and analgesia treatment. It will provide new thoughts and a safe and appropriate method for the application of ketamine in perioperative anesthesia.
文章引用:徐锐, 李晓霞. 艾司氯胺酮在围术期麻醉应用的研究进展[J]. 临床医学进展, 2023, 13(4): 6203-6210. https://doi.org/10.12677/ACM.2023.134874

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