柴胡疏肝散合左金丸治疗肝胃郁热型反流性食管炎的研究进展

Research Progress of Chaihu Shugan San Combined with Zuojinwan in Treating Reflux Esophagitis of Liver and Stomach Stagnation Heat Type

摘要: 近年来随着人们生活水平的提高，和生活的不规律，导致反流性食管炎的发病率逐年升高，虽然西医在治疗本病取得了一定进步，但仍然没有突破性进展，长期用药或停药后有其局限性。经过文献查询，发现在中医学中，反流性食管炎主要以肝胃郁热型为主，同时发现柴胡疏肝散合左金丸对于肝胃郁热型有良好的治疗效果，但缺乏对文献的整理，导致合方的价值没能被进一步地挖掘。因此本文从肝胃郁热型反流性食管炎的病因病机、治疗方法，和柴胡疏肝散合左金丸的临床研究、药理分析出发，总结合方治疗上述疾病的文献支持。

Abstract: In recent years, with the improvement of people’s living standards and irregular life, the incidence of reflux esophagitis has increased year by year. Although Western medicine has made certain progress in the treatment of this disease, there is still no breakthrough, and its limitations after long-term drug use or withdrawal. Through literature search, it is found that in traditional Chinese medicine, reflux esophagitis is mainly dominated by heat stagnation of liver and stomach. Meanwhile, it is found that Chaihu Shugan Powder combined with Zuojin Wan has a good therapeutic effect on heat stagnation of liver and stomach. However, the lack of literature review leads to the failure to further explore the value of the combined prescription. Therefore, this paper starts from the etiology, pathogenesis and treatment of reflux esophagitis caused by stagnation of liver and stomach, as well as the clinical research and pharmacological analysis of Chaihu Shugan Powder combined with Zuojin Pills, and provides literature support for the total combination prescription in the treatment of the above diseases.