支气管哮喘发病机制的研究新进展
New Advances in the Study of the Pathogenesis of Bronchial Asthma
DOI: 10.12677/ACM.2023.134927, PDF,   
作者: 吴志豪：青海大学临床医学院，青海 西宁 ；曹海霞*：青海大学附属医院儿科，青海 西宁
关键词: 支气管哮喘；发病机制；研究进展；Bronchial Asthma； Pathogenesis； Research Progress
摘要: 支气管哮喘(简称哮喘)是由多种因素综合影响所致的以气道重塑、气道高反应性和气道慢性炎症为特征的一种异质性疾病，严重影响了患者的身心健康以及生活质量。近年来，国内外关于支气管哮喘发病机制的研究取得了重大进展，本文重点从外源性发病因素(包括生物因素、生态环境因素、营养因素、社会–心理因素)以及内源性发病因素(包括免疫因素、遗传因素)总结支气管哮喘发病机制的新发现，以期为哮喘的进一步研究及潜在问题提供帮助。
Abstract: Bronchial asthma (asthma) is a heterogeneous disease characterized by airway remodeling, airway hyperresponsiveness and chronic airway inflammation caused by a combination of factors, which seriously affects the physical and mental health as well as the quality of life of patients. In recent years, significant progress has been made in the research on the pathogenesis of bronchial asthma at home and abroad. In this paper, we focus on the new findings on the pathogenesis of bronchial asthma from exogenous pathogenic factors (including biological factors, ecological and environ-mental factors, nutritional factors, and socio-psychological factors) and endogenous pathogenic fac-tors (including immune factors and genetic factors), in order to provide help for further research and potential problems of asthma.
文章引用：吴志豪, 曹海霞. 支气管哮喘发病机制的研究新进展[J]. 临床医学进展, 2023, 13(4): 6623-6630. https://doi.org/10.12677/ACM.2023.134927

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