剪切力对血管内皮功能影响的研究进展
Research Progress of the Effect of Shear Stress on Vascular Endothelial Cells Function
DOI: 10.12677/ACM.2023.1351010, PDF,   
作者: 目接色木·卡德尔, 陈春玲*:新疆医科大学第一附属医院麻醉科,新疆 乌鲁木齐
关键词: 剪切力血管内皮细胞内皮细胞糖萼层Shear Stress Vascular Endothelial Cells Endothelial Cells Glycocalyx
摘要: 流动的血液不断地对血管壁内的内皮细胞施加摩擦力,为剪切应力。生理水平的剪切力作用于血管内皮细胞,而血管内皮细胞通过改变其形态、功能和基因表达来响应剪切应力。生理水平的剪切力在保护血管内皮细胞功能方面具有重大意义。因此,本文介绍了剪切力与血管内皮细胞,从剪切力对血管内皮细胞作用机制到内皮细胞糖萼层的作用方面进行了综述。
Abstract: The flow of blood constantly exerts friction on the endothelial cells in the blood vessel wall, which is shear stress. Physiological shear stress is applied to vascular endothelial cells, which respond to shear stress by changing their morphology, function, and gene expression. Physiological shear force plays an important role in protecting the function of vascular endothelial cells. Therefore, this re-view introduces shear stress and vascular endothelial cells, and reviews the mechanism of shear force on vascular endothelial cells and the effect of endothelial cells on glycocalyx layer.
文章引用:目接色木·卡德尔, 陈春玲. 剪切力对血管内皮功能影响的研究进展[J]. 临床医学进展, 2023, 13(5): 7227-7231. https://doi.org/10.12677/ACM.2023.1351010

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