结核性胸膜炎实验室检查的研究进展

Research Progress in Laboratory Examination of Tuberculous Pleurisy

摘要: 结核性胸膜炎是最常见的肺外结核形式，常需要与恶性或其他感染性疾病相鉴别。但由于胸腔积液或胸膜结核分枝杆菌检出率较低，有时需结合症状、病理学及生物标志物等进行临床综合诊断。目前为止，针对结核性胸膜炎诊断的研究众多，其中免疫学与分子生物学在结核病诊断领域广泛应用，为结核性胸膜炎诊断提供新的途径。值得注意的是，目前单独应用这些方法的诊断效能尚不尽人意，但联合使用多种方法可提高其诊断性能。

Abstract: Tuberculous pleurisy, the most common form of extrapulmonary tuberculosis, is often needed to be distinguished from malignant or other infectious diseases. However, because of its low detection rate of pleural effusion or pleural tuberculosis, a comprehensive clinical diagnosis is sometimes re-quired in combination with symptoms, pathology and biomarkers. So far, numerous studies have been conducted for the diagnosis of tuberculous pleurisy, among which immunology and molecular biology are widely used in tuberculosis diagnosis, providing a new way for the diagnosis of tubercu-lous pleurisy. It is worth noting that the diagnostic efficacy of these methods alone is not yet satis-factory, but the combined use of multiple methods can improve their diagnostic performance.