电化学交流阻抗技术在医学检验中的研究应用
The Application of Electrochemical Impedance Technique in Medical Detection: A Review
DOI: 10.12677/AAC.2023.132021, PDF,    国家自然科学基金支持
作者: 杭宇腾, 李一隆, 刘 帅, 陈冠烨:南通大学公共卫生学院,江苏 南通;管小荣:江苏奥威信息系统工程有限公司,江苏 南通;刘 扬*:南通大学公共卫生学院,江苏 南通;江苏奥威信息系统工程有限公司,江苏 南通
关键词: 电化学阻抗谱医学检验生物传感器EIS Medical Detection Biosensor
摘要: 电化学阻抗谱(Electrochemical Impedance Spectroscopy,简称EIS)可以用于分析电极表面与生物识别事件相关的界面特性,如抗原抗体反应、氧化还原反应、电子交换等。随着电极制造工艺和纳米材料的发展,基于EIS技术的电化学传感器广泛应用于生物检测。本文将从EIS技术的基本原理、工作电极的研究进展的角度入手,总结了EIS技术在心血管疾病、肿瘤标志物测定、细菌病毒感染和蛋白质检测等医学检测的最新进展,以及基于EIS技术的生物传感器在商品化和快速检测方面的发展趋势。
Abstract: Electrochemical impedance spectroscopy (EIS) can be used to analyze the interfacial properties of electrode surfaces related to biological recognition events, such as antigen-antibody reactions, redox reactions, electron exchange, etc. With the development of electrode fabrication process and nanomaterials, electrochemical sensors based on EIS technology are widely used in bio-detec- tion. In this paper, we will summarize the latest progress of EIS technology in medical testing such as cardiovascular diseases, tumor marker determination, bacterial and viral infections and protein detection, as well as the development trend of EIS technology-based biosensors in commercialization and rapid detection from the perspective of the basic principles of EIS technology and the research progress of working electrodes.
文章引用:杭宇腾, 李一隆, 刘帅, 陈冠烨, 管小荣, 刘扬. 电化学交流阻抗技术在医学检验中的研究应用[J]. 分析化学进展, 2023, 13(2): 171-180. https://doi.org/10.12677/AAC.2023.132021

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