周恩超教授从“毒”论治慢性肾衰竭临床观察

Clinical Observation on Professor Zhou Enchao’s Experience in Treating Chronic Renal Failure from “Poison”

摘要: 目的：探讨苏茵解毒方治疗慢性肾衰竭的临床疗效。方法：选择2019年8月至2021年12月收治的慢性肾功能衰竭患者60例，随机分为对照组和观察组，各30例，对照组予以药用炭治疗，观察组予以苏茵解毒方治疗，比较两组治疗前后的临床疗效。结果：观察组治疗有效率为86.66%，远高于对照组的63.33% (P < 0.05)。治疗后两组的BUN、Scr水平均低于治疗前，观察组明显低于对照组(P < 0.01)；eGFR水平高于治疗前，观察组高于对照组(P < 0.05)；治疗后中医症状积分较对照组显著降低(P < 0.05)。两组治疗前后均无不良反应。结论：周恩超教授经验方治疗慢性肾衰疗效确切，可显著改善患者肾功能和临床症状，用药安全。

Abstract: Objective: To investigate the clinical effect of Suyin Jiedu prescription on chronic renal failure. Methods: A total of 60 patients with chronic renal failure admitted from August 2019 to December 2021 were randomly divided into control group (n = 30) and observation group (n = 30). The con-trol group was treated with medicinal charcoal, and the observation group was treated with Suyin Jiedu prescription. The clinical efficacy of the two groups before and after treatment was compared. Results: The effective rate of the observation group was 86.66%, which was much higher than the control group (63.33%, P < 0.05). BUN and Scr levels of the two groups after treatment were lower than before treatment, and the observation group was lower than the control group, eGFR level was higher than before treatment, and the observation group was higher than the control group (P < 0.05). After treatment, TCM symptom score was significantly decreased compared with control group (P < 0.05). There were no adverse reactions before and after treatment in both groups. Con-clusion: Professor Zhou Enchao’s empirical prescription is effective in the treatment of chronic renal failure, can significantly improve renal function and clinical symptoms of patients, and the medica-tion is safe.