缺血性脑卒中后癫痫发作的相关危险因素分析

Analysis of Related Risk Factors of Epileptic Seizure after Ischemic Stroke

摘要: 目的：分析缺血性卒中后癫痫发作的临床特点，探究脑卒中癫痫发作的相关危险因素，以提供更多有意义的临床诊疗资料。方法：通过回顾性研究癫痫发作时间、发作类型、脑电图等记录。病例资料为选取青大附院神经内科2017年06月~2018年06月住院的缺血性卒中患者作为研究对象，对缺血性卒中后癫痫发作患者的临床特点进行分析。结果：1) 癫痫发生率为3.9%。2) 局灶性发作(知觉保留)占27%，局灶性发作(知觉损害)占5%，局灶性进展为双侧强直–阵挛性占30%，全面性发作占37.5%。3) 高NIHSS评分、吸烟、男性发病的占比高。结论：1) 全面性发作为最常见的发作分型，然后是局灶性进展的双侧强直阵挛性发作。2) 卒中病人中继发性癫痫的危险因素有：性别，卒中轻重，抽烟。

Abstract: Objective: To analyze the clinical characteristics of epileptic seizure after ischemic stroke, and ex-plore the risk factors related to epileptic seizure after stroke, in order to provide more meaningful clinical diagnosis and treatment data. Methods: The seizure time, seizure type and EEG were stud-ied retrospectively. Patients with ischemic stroke who were hospitalized in the Department of Neu-rology of the Affiliated Hospital of Youth University from June 2017 to June 2018 were selected as the research objects to analyze the clinical characteristics of patients with epileptic seizure after is-chemic stroke. Results: 1) The incidence of epilepsy was 3.9%. 2) Focal seizures (retention of per-ception) accounted for 27%, focal seizures (impairment of perception) accounted for 5%, focal pro-gression to bilateral tonic-clonus accounted for 30%, and generalized seizures accounted for 37.5%. 3) High NIHSS score, smoking and male morbidity accounted for a high proportion. Conclusions: 1) Generalized seizures were the most common seizure type, followed by bilateral tonic-clonic seizures with focal progression. 2) Risk factors for secondary epilepsy in stroke patients include gender, se-verity of stroke, and smoking.