肌肉减少症研究进展

Research Progress of Sarcopenia

摘要: 肌肉减少症(sarcopenia) (简称肌少症)是一种进行性和全身性骨骼肌疾病，涉及肌肉力量减低、肌肉质量下降和躯体功能的加速丧失，与跌倒、功能衰退、虚弱和死亡率等不良后果增加有关，分为与年龄相关的原发性肌肉减少症及由慢性疾病所致的继发性肌肉减少症。随着世界人口的老龄化，肌少症的患病率总体来说呈上升趋势。因此，早期识别并采取有效干预措施延缓肌少症的发生十分必要。本文从肌少症的概念、发病机制、合并常见慢性病等方面进行综述，旨在提高临床工作者对肌少症的认识从而提高老年人群生活质量、减轻医疗保健系统的负担。

Abstract: Sarcopenia (abbreviated as sarcopenia) is a progressive and systemic skeletal muscle disease that involves decreased muscle strength, decreased muscle mass, and accelerated loss of physical func-tion. It is associated with increased adverse consequences such as falls, functional decline, weak-ness, and mortality. It can be divided into age-related primary sarcopenia and secondary sarcope-nia caused by chronic diseases. With the aging of the world population, the overall incidence of sar-copenia is on the rise. Therefore, early identification and effective intervention measures are nec-essary to delay the occurrence of sarcopenia. This article reviews the concept, pathogenesis, and common chronic diseases of sarcopenia, aiming to enhance clinical workers’ understanding of sar-copenia, improve the quality of life of the elderly population, and reduce the burden on the healthcare system.