痤疮后红斑的局部治疗进展
Progression of Local Treatment of Post-Acne Erythema
DOI: 10.12677/ACM.2023.1361287, PDF,   
作者: 涂 莉:青海大学研究生院,青海 西宁 ;马文宇:青海大学附属医院,青海 西宁
关键词: 痤疮后红斑马来酸噻吗洛尔氨甲环酸治疗Post-Acne Erythema Timolol Maleate TXA Treatment
摘要: 面部痤疮炎症性皮损如丘疹、脓疱、结节和囊肿愈合后会遗留褐红色的炎症后红斑,炎症后红斑又称痤疮后红斑。痤疮后红斑是常见的痤疮后遗皮损,由于痤疮后红斑皮损位于面部,会对患者社会交往产生影响,从而导致自卑等心理改变,患者的治疗愿望非常强烈。痤疮后红斑的治疗方法多种多样,包括局部治疗、光电治疗等,本文将结合国内外研究对痤疮后红斑的局部治疗进展进行综述。
Abstract: Inflammatory skin lesions of facial acne such as papules, pustules, nodules, and cysts leave a brownish-red post-inflammatory erythema, also known as post-acne erythema. Post-acne erythema is a common post-acne lesion, and because the post-acne erythema lesion is located on the face, it will have an impact on the patient’s social interaction, resulting in psychological changes such as low self-esteem, and the patient’s desire for treatment is very strong. There are various treatments for post-acne erythema, including topical treatment and photoelectric therapy, and this article will review the progress of local treatment of post-acne erythema in combination with domestic and for-eign research.
文章引用:涂莉, 马文宇. 痤疮后红斑的局部治疗进展[J]. 临床医学进展, 2023, 13(6): 9188-9193. https://doi.org/10.12677/ACM.2023.1361287

参考文献

[1] 鞠强. 中国痤疮治疗指南(2019修订版) [J]. 临床皮肤科杂志, 2019, 48(9): 583-588.
[2] Wanitphakdeedecha, R., et al. (2020) The Efficacy and Safety of a 577-nm High-Power Optically Pumped Semiconductor Laser in the Treatment of Postacne Erythema. Journal of Cosmetic Dermatology, 19, 1642-1647. [Google Scholar] [CrossRef] [PubMed]
[3] Ji, J., et al. (2018) Correlations of SOX9 Expression with Serum IGF1 and Inflammatory Cytokines IL-1α and IL-6 in Skin Lesions of Patients with Acne. European Review for Medical and Pharmacological Sciences, 22, 2549-2555.
[4] Kalantari, Y., Dadkhahfar, S. and Etesami, I. (2022) Post-Acne Ery-thema Treatment: A Systematic Review of the Literature. Journal of Cosmetic Dermatology, 21, 1379-1392. [Google Scholar] [CrossRef] [PubMed]
[5] Weibel, L., et al. (2016) Topical Timolol for Infantile Hemangiomas: Evi-dence for Efficacy and Degree of Systemic Absorption. Pediatric Dermatology, 33, 184-190. [Google Scholar] [CrossRef] [PubMed]
[6] Muñoz-Garza, F.Z., et al. (2021) Efficacy and Safety of Topical Timolol for the Treatment of Infantile Hemangioma in the Early Proliferative Stage: A Randomized Clinical Trial. JAMA Dermatology, 157, 583-587. [Google Scholar] [CrossRef] [PubMed]
[7] 李琳, 宋俐, 王胜春, 王胜, 于建斌. 马来酸噻吗洛尔滴眼液治疗婴幼儿血管瘤125例临床观察[J]. 中国皮肤性病学杂志, 2016, 30(1): 36-38.
[8] Afra, T.P., Razmi, T.M. and De, D. (2021) Topical Timolol for Postacne Erythema. Journal of the American Academy of Dermatology, 84, e255-e256. [Google Scholar] [CrossRef] [PubMed]
[9] Del Rosso, J.Q. and Tanghetti, E. (2021) Topical Ox-ymetazoline Hydrochloride Cream 1% for the Treatment of Persistent Facial Erythema of Rosacea in Adults: A Compre-hensive Review of Current Evidence. Journal of Clinical and Aesthetic Dermatology, 14, 32-37.
[10] Agamia, N., Es-sawy, M. and Kassem, A. (2022) Successful Treatment of the Face Post Acne Erythema Using a Topically Applied Se-lective Alpha 1-Adrenergic Receptor Agonist, Oxymetazoline 1.5%, a Controlled Left to Right Face Comparative Trial. Journal of Dermatological Treatment, 33, 904-909. [Google Scholar] [CrossRef] [PubMed]
[11] Washrawirul, C., et al. (2023) The Role of the Topical Nasal Decongestant Oxymetazoline as a Novel Therapeutic Option for Post-Acne Erythema: A Split-Face, Double-Blind, Ran-domized, Placebo-Controlled Trial. The Journal of Dermatology. [Google Scholar] [CrossRef] [PubMed]
[12] Elnagdy, S.A.E. (2021) A Comparative Study Between Some Therapeutic Approaches for the Treatment of Post Acne Erythema. ALEXMED ePosters, 3, 27-28. [Google Scholar] [CrossRef
[13] Piwnica, D., et al. (2014) Vasoconstriction and An-ti-Inflammatory Properties of the Selective α-Adrenergic Receptor Agonist Brimonidine. Journal of Dermatological Sci-ence, 75, 49-54. [Google Scholar] [CrossRef] [PubMed]
[14] Genedy, R.M. (2016) Topical Brimonidine Tartrate as a Novel Treatment for Facial Erythema of Rosacea and Acne Erythema. Journal of the Egyptian Women’s Dermatologic Society, 13, 55-64. [Google Scholar] [CrossRef
[15] Okwundu, N., Cline, A. and Feldman, S.R. (2021) Difference in Vasoconstrictors: Oxymetazoline vs. Brimonidine. Journal of Dermatological Treatment, 32, 137-143. [Google Scholar] [CrossRef] [PubMed]
[16] Li, Y., et al. (2019) Tranexamic Acid Ameliorates Rosacea Symptoms through Regulating Immune Response and Angiogenesis. International Immunopharmacology, 67, 326-334. [Google Scholar] [CrossRef] [PubMed]
[17] Jakhar, D. and Kaur, I. (2020) Topical 5% Tranexamic Acid for Acne-Related Postinflammatory Erythema. Journal of the American Academy of Dermatology, 82, e187-e188. [Google Scholar] [CrossRef] [PubMed]
[18] Agamia, N., El-Nagdy, S. and El-Ariny, A. (2022) A Split Face Comparative Study Using a Novel Triple Combination Therapy for the Treatment of Persistent Post Acne Erythema. Dermatologic Therapy, 35, e15327. [Google Scholar] [CrossRef] [PubMed]
[19] Mhatre, M., Sharma, A. and Agrawal, S. (2022) Topical Tacrolimus for Acne-Related Macular Erythema to Prevent Atrophic Scarring. Journal of the American Academy of Dermatology, 86, e253-e254. [Google Scholar] [CrossRef] [PubMed]
[20] Kurokawa, I., Watanabe, M. and Hayashibe, K. (2020) Effect of a Cosmetic Use with 2% Isostearyl-L-Ascorbic Acid Gel for Postinflammatory Hyperpigmentation and Postinflammatory Erythema in Acne Vulgaris. Journal of Cosmetics, Dermatological Sciences and Applications, 10, 28-32. [Google Scholar] [CrossRef
[21] Jaros, A., et al. (2019) Evaluation of Selected Skin Parameters Following the Application of 5% Vitamin C Concentrate. Journal of Cosmetic Dermatology, 18, 236-241. [Google Scholar] [CrossRef] [PubMed]
[22] Kurokawa, I., Yoshioka, M. and Ito, S. (2019) Split-Face Comparative Clinical Trial Using Glyceryl-Octyl-Ascorbic Acid/ascorbyl 2-Phosphate 6-Palmitate/DL-α-Tocopherol Phosphate Com-plex Treatment for Postinflammatory Hyperpigmentation, Postinflammatory Erythema and Atrophic Scar in Acne Vul-garis. The Journal of Dermatology, 46, e347-e348. [Google Scholar] [CrossRef] [PubMed]
[23] Draelos, Z.D., Ertel, K. and Berge, C. (2005) Niacina-mide-Containing Facial Moisturizer Improves Skin Barrier and Benefits Subjects with Rosacea. Cutis, 76, 135-141.
[24] Rolfe, H.M. (2014) A Review of Nicotinamide: Treatment of Skin Diseases and Potential Side Effects. Journal of Cosmetic Dermatology, 13, 324-328. [Google Scholar] [CrossRef] [PubMed]
[25] Carneiro, R., et al. (2011) Topical Emulsions Containing Ceramides: Effects on the Skin Barrier Function and Anti-Inflammatory Properties. Euro-pean Journal of Lipid Science and Technology, 113, 961-966. [Google Scholar] [CrossRef
[26] Sparavigna, A., Tenconi, B. and De Ponti, I. (2014) Preliminary Open-Label Clinical Evaluation of the Soothing and Reepithelialization Properties of a Novel Topical Formulation for Rosacea. Clinical, Cosmetic and Investigational Dermatology, 7, 275-283. [Google Scholar] [CrossRef