针刺合谷穴脑功能磁共振成像的研究进展

Research Progress of Functional Brain Magnetic Resonance Imaging of Acupuncture Hegu Point

摘要: 目的：通过查阅针刺合谷穴脑功能磁共振成像(fMRI)技术研究的相关文献，进行现状的总结归纳思考，提出问题与展望。方法：运用中国知网、PubMed等数据库，以“针刺and合谷穴and功能磁共振成像”“zhenci and heguxue and fMRI”为检索词进行检索，对文章进行筛选、总结和分析。结果：1) 针刺合谷穴激活脑区的特异性；2) 针刺合谷穴在生理和病理状态下激活脑区的差异；3) 针刺合谷镇痛的机制。结论：针刺合谷穴可特异性激活大脑皮层语言运用中枢、面部反应区、听觉皮区，与合谷穴主治基本吻合，边缘–旁脑–新皮质网络脑功能的激活可能与合谷用于镇痛的作用密切相关。

Abstract: Objective: To summarize and consider the current status of the research on functional magnetic resonance imaging (fMRI) of the brain at the acupuncture point of Hegu by reviewing the relevant literature, and to raise questions and prospects. Methods: Using the databases of China Knowledge Network and PubMed, the articles were searched with the search terms of “acupuncture and hegu acupuncture point and functional magnetic resonance imaging”, “zhenci and heguxue and fMRI”. The articles were screened, summarized and analyzed. Results: 1) Specificity of activation of brain regions by acupuncture at the Hegu acupoint; 2) Differences in activation of brain regions by acu-puncture at the Hegu acupoint in physiological and pathological states; 3) Mechanisms of analgesia by acupuncture at the Hegu. Conclusions: Acupuncture at the Hegu point can specifically activate the cortical language use center, facial response area, and auditory cortex, which is consistent with the main treatment of the Hegu point, and the activation of the limbic-paracortical-neocortical net-work may be closely related to the analgesic effect of Hegu.