依达拉奉右莰醇在缺血性脑卒中的研究进展
Research Progress of Edaravone and Dextranol in Ischemic Stroke
DOI: 10.12677/ACM.2023.1361390, PDF,   
作者: 周 文：青海大学研究生院，青海 西宁；赵秀丽*：青海大学附属医院神经内科，青海 西宁
关键词: 依达拉奉右坎醇；缺氧性脑卒中；作用机制；Edaravone-Dexborneol； Ischemic Stroke； Mechanism of Action
摘要: 缺血性脑卒中(Ischemic Stroke, IS)是我国成年人致残、致死的首位疾病，其损伤机制复杂。目前，静脉溶栓、动脉取栓是缺血性脑卒中脑血管再通的重要方法，但由于治疗时间窗的限制，只有不到5%的患者能够接受脑血管再通治疗。我国自主研发的1类新药依达拉奉右莰醇(edaravone-dexborneol)是由依达拉奉和右莰醇以4:1的比例组成的神经保护剂，用于改善缺血性脑卒中所致的神经功能障碍。本文将概述依达拉奉右莰醇在缺血性脑卒中的作用机制，为其治疗缺血性脑卒中的治疗提供理论依据。
Abstract: Ischemic stroke (IS) is the leading cause of adult disability and death in our country. At present, in-travenous thrombolysis and arterial thrombectomy are important methods for cerebral vascular recanalization in ischemic stroke. However, less than 5% of patients with ischemic stroke can be treated with recanalization because of the treatment time window (<4.5 hours). Edara-vone-dexborneol, a new drug developed in our country, is a neuroprotective agent composed of edaravone and dexborneol in a ratio of 4:1. This article will summarize the mechanism of edaravone right camphor in the treatment of ischemic stroke, and provide theoretical basis for its treatment of ischemic stroke.
文章引用：周文, 赵秀丽. 依达拉奉右莰醇在缺血性脑卒中的研究进展[J]. 临床医学进展, 2023, 13(6): 9947-9951. https://doi.org/10.12677/ACM.2023.1361390

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