LncRNAs在胰腺癌中的作用及研究现状
The Role and Research Status of LncRNAs in Pancreatic Cancer
DOI: 10.12677/ACM.2023.1361423, PDF,   
作者: 黄 劲, 张 莉*：新疆医科大学干部保健中心，新疆 乌鲁木齐
关键词: 长链非编码RNA；胰腺癌；耐药；Long-Stranded Non-Coding RNA； Pancreatic Cancer； Drug Resistance
摘要: 目的：胰腺癌因治疗和预后效果极差而被称为癌症之王，目前在科研层面也难以攻克。本研究阐明了LncRNA在胰腺癌进展及耐药过程中的作用机理，为研究人员寻找检测和治疗胰腺癌的靶点提供相关的思路。方法：通过查阅大量国内外文献，以确定评估非编码RNA在胰腺癌中的作用或胰腺癌与LncRNA之间关系。结论：将胰腺癌发展的不同阶段与LncRNA相对应，以及使用LncRNA所参与的信号通路相应药物，或许对于早期筛查及针对不同分期的病人靶向治疗具有一定意义。
Abstract: Objective: Pancreatic cancer is known as the king of cancer due to poor treatment and prognosis, and it is difficult to overcome in scientific research. This paper describes the mechanism of non-coding RNA in the progression and drug resistance of pancreatic cancer, which provides some ideas for researchers to find targets for detection and treatment of pancreatic cancer. Methods: The role of non-coding RNA in pancreatic cancer or the relationship between pancreatic cancer and LncRNA was evaluated by reviewing a large number of domestic and foreign literatures. Conclusions: The correlation between different stages of pancreatic cancer development and LncRNA, as well as the corresponding drugs in the signaling pathway involved in the use of LncRNA, may have certain significance for early screening and targeted therapy for patients at different stages.
文章引用：黄劲, 张莉. LncRNAs在胰腺癌中的作用及研究现状[J]. 临床医学进展, 2023, 13(6): 10170-10174. https://doi.org/10.12677/ACM.2023.1361423

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