脑卒中发病部位与睡眠障碍相关性研究

Study on Correlation between Stroke Lesion Site and Sleep Disorder

摘要: 目的：分析脑卒中部位患者睡眠障碍发病相关性。方法：选取2021年7月至2023年2月在福建中医药大学附属第二人民医院就诊的符合标准的急性脑卒中患者205例急性脑卒中患者，其中男134例，女71例，年龄在44~85岁，平均(67.39 ± 10.97)岁，根据患者是否出现睡眠障碍症状进行分组，其中81例患者为睡眠障碍组，124例患者为非睡眠障碍组。对两组患者的病灶发生部位进行研究分析，主要包括患者的小脑部、脑干部、丘脑部、左半球部、右半球部、基底节部。结果：睡眠障碍组患者病灶发生部位以脑干部、丘脑部为主，构成比分别为25.93% (21/81)、19.75% (16/81)，显著高于非睡眠障碍组，检验P < 0.05。通过Logistic回归分析，病灶发生于脑干部(OR = 2.988, P = 0.005)以及丘脑(OR = 2.529, P = 0.028)是导致急性脑卒中患者睡眠障碍的相关因素。结论：急性脑卒中病灶发生部位集中于脑干部以及丘脑部时，临床上需引起重视，及时予以中西医治疗睡眠障碍，以期获得良好预后。

Abstract: Objective: To analyze the correlation of sleep disorders in patients with stroke. Methods: Selection of 205 cases for the period July 2021 to February 2023, the cases were from the Second People’s Hospital Affiliated to Fujian Traditional Chinese Medicine University treated pa-tients with acute stroke, including 134 males and 71 females, aged 44~85 years, with an average age of (67.39 ± 10.97) years. The patients were grouped according to whether they had symptoms of sleep disorders. Among them, 81 patients were in the sleep disorder group and 124 patients were in the non-sleep disorder group. The sites of lesions in the two groups were studied and ana-lyzed, including the small brain, brain cadre, thalamus, left hemisphere, right hemisphere, and ba-sal ganglia of patients. Results: The brain cadre and thalamus were the main sites of the lesions in the sleep disorder group; the composition ratios were 25.93% (21/81) and 19.75% (16/81), re-spectively, which were significantly higher than those in the non-sleep disorder group, P < 0.05. Lo-gistic regression analysis showed that the lesions occurred in brain cadres (OR = 2.988, P = 0.005) and thalamus (OR = 2.529, P = 0.028) was associated with sleep disorders in patients with acute stroke. Conclusion: When acute stroke lesions are concentrated in the brain cadre and thalamus, attention should be paid to the clinical treatment of sleep disorders with Chinese and Western medicine in time, in order to obtain a good prognosis.