垂体柄阻断综合征的诊断学特征并文献复习

Diagnostic Features of Pituitary Stalk Block-ade Syndrome and Review of the Literature

摘要: 目的：探讨垂体柄阻断综合征(PSIS)诊断学特征。方法：回顾性分析2022年3月4日济宁市第一人民医院内分泌科收治的1例44岁终确诊为PSIS患者的临床资料，并进行文献复习。结果：患者女性，44岁，因“生长发育迟缓30余年，恶心、呕吐4天”入院，身高151 cm，体重35 kg，血压90/64 mmHg，双侧乳腺Tanner II期，幼稚外阴，阴毛Tanner I期，左左腕关节骨龄片13.6岁，垂体MRI提示腺垂体变小、垂体柄显示不清、神经垂体异位，诊断为PSIS。结论：临床上对生长发育迟缓的患者，需警惕PSIS的可能，避免漏诊。

Abstract: Objective: To investigate the diagnostic characteristics of pituitary stalk interruption syndrome (PSIS). Methods: The clinical data of a 44-year-old patient diagnosed with PSIS admitted to the De-partment of Endocrinology, Jining First People’s Hospital on March 4, 2022 were retrospectively an-alyzed, and the literature was reviewed. Results: A 44-year-old female patient was admitted to the hospital due to “growth retardation for more than 30 years, nausea and vomiting for 4 days”. The height was 151 cm, the weight was 35 kg, the blood pressure was 90/64 mmHg, bilateral breast Tanner stage II, immature vulva, pubic hair Tanner stage I, left wrist bone age film 13.6 years old, pituitary MRI showed that the adenohypophysis became smaller, the pituitary stalk was unclear, and the neurohypophysis was ectopic. The diagnosis was PSIS. Conclusion: Clinically, patients with growth retardation should be alert to the possibility of PSIS and avoid missed diagnosis.