老年人高血压临床治疗研究进展
Research Progress on Clinical Treatment of Hypertension in the Elderly
DOI: 10.12677/ACM.2023.1371573, PDF,   
作者: 侯俊宁, 张 颖*：新疆医科大学第一附属医院，新疆 乌鲁木齐
关键词: 老年高血压；临床治疗；Elderly Hypertension； Clinical Treatment
摘要: 高血压作为心血管系统疾病中常见且严重的疾患，针对其研究也越来越深入，其中老年高血压正成为研究的热点话题，社会老龄化问题加剧，使得老年高血压的发病率上升。因此了解国内外研究现状对老年高血压的诊疗有指导意义。本文就老年高血压治疗的关键问题进行阐述。
Abstract: Hypertension is a common and serious disease in the cardiovascular system, and its research is get-ting more and more in-depth. Among them, hypertension in the elderly is becoming a hot topic of research. The problem of aging society is intensifying, which makes the incidence of hypertension in the elderly increase. Therefore, understanding the current research status at home and abroad has guiding significance for the diagnosis and treatment of elderly hypertension. This article elaborates on the key issues in the treatment of hypertension in the elderly.
文章引用：侯俊宁, 张颖. 老年人高血压临床治疗研究进展[J]. 临床医学进展, 2023, 13(7): 11261-11265. https://doi.org/10.12677/ACM.2023.1371573

参考文献

[1] Benetos, A., Petrovic, M. and Strandberg, T. (2019) Hypertension Management in Older and Frail Older Patients. Cir-culation Research, 124, 1045-1060. [Google Scholar] [CrossRef] 
[2] 邓思均, 梁登攀. 高龄老年高血压的研究进展[J]. 四川医学, 2022, 43(10): 1041-1044.
[3] 田昕彤, 马腾, 孙璇, 等. 老年高血压临床指南现状分析及质量评价[J]. 中国全科医学, 2022, 25(34): 4259- 4266+4285.
[4] Liu, P., Li, Y., Zhang, Y., et al. (2020) Frailty and Hypertension in Older Adults: Current Understanding and Future Perspectives. Hypertension Research, 43, 1352-1360. [Google Scholar] [CrossRef] [PubMed]
[5] 刘真秀, 董铭, 林立文, 等. 《中国老年高血压管理指南2019》解读[J]. 长春中医药大学学报, 2020, 36(5): 1076-1079.
[6] Kjeldsen, S.E., Stenehjem, A., Os, I., et al. (2016) Treatment of High Blood Pressure in Elderly and Octogenarians: European Society of Hypertension Statement on Blood Pressure Targets. Blood Pressure, 25, 333-336. [Google Scholar] [CrossRef] [PubMed]
[7] 于华. 老年高血压患者动态血压与靶器官损害相关性[J]. 中国老年学杂志, 2015, 35(18): 5314-5315.
[8] 杨凯悦, 侯慧卿, 底佳倩, 等. 老年高血压肾损害早期识别及治疗的研究进展[J]. 河北医药, 2022, 44(7): 1088- 1092.
[9] O’Rourke, M.F., Namasivayam, M. and Adji, A. (2009) Treatment of Hypertension in Patients 80 Years of Age or Older. Minerva Medica, 100, 25-38. [Google Scholar] [CrossRef] 
[10] 李瑾, 刘江峰, 符赵鑫. 不同种类美托洛尔片联合依那普利治疗老年高血压合并心力衰竭患者的疗效及安全性[J]. 山西医药杂志, 2022, 51(12): 1377-1380.
[11] Streit, S., Poortvliet, R.K.E. and Gussekloo, J. (2018) Lower Blood Pressure during Antihypertensive Treatment Is Associated with Higher All-Cause Mortality and Accelerated Cognitive Decline in the Oldest-Old. Data from the Leiden 85-plus Study. Age Ageing, 47, 545-550. [Google Scholar] [CrossRef] [PubMed]
[12] Masoli, J.A.H., Delgado, J., Pilling, L., et al. (2020) Blood Pressure in Frail Older Adults: Associations with Cardiovascular Outcomes and All-Cause Mortality. Age Ageing, 49, 807-813. [Google Scholar] [CrossRef] [PubMed]
[13] 胡芳英, 方红薇, 林萍, 等. 抗高血压治疗后肌酐水平升高对患者心血管事件发生率的影响研究[J]. 中华全科医学, 2022, 20(7): 1147-1150.
[14] Lewis, C.E., Fine, L.J., Beddhu, S., et al. (2021) Final Report of a Trial of Intensive versus Standard Blood-Pressure Control. The New England Journal of Medicine, 384, 1921-1930. [Google Scholar] [CrossRef] 
[15] Materson, B.J., Garcia-Estrada, M. and Preston, R.A. (2016) Hypertension in the Frail Elderly. Journal of the American Society of Hypertension, 10, 536-541. [Google Scholar] [CrossRef] [PubMed]
[16] Zhang, X.E., Cheng, B. and Wang, Q. (2016) Relationship between High Blood Pressure and Cardiovascular Outcomes in Elderly Frail Patients: A Systematic Review and Meta-Analysis. Geriatric Nursing, 37, 385-392. [Google Scholar] [CrossRef] [PubMed]
[17] Kang, M.G., Kim, S.W., Yoon, S.J., et al. (2017) Association between Frailty and Hypertension Prevalence, Treatment, and Control in the Elderly Korean Population. Scientific Reports, 7, Article No. 7542. [Google Scholar] [CrossRef] [PubMed]
[18] Gijón-Conde, T., Graciani, A., López-García, E., et al. (2018) Frailty, Disability, and Ambulatory Blood Pressure in Older Adults. Journal of the American Medical Directors Associa-tion, 19, 433-438. [Google Scholar] [CrossRef] [PubMed]
[19] Orkaby, A.R., Lunetta, K.L., Sun, F.J., et al. (2019) Cross-Sectional Association of Frailty and Arterial Stiffness in Community-Dwelling Older Adults: The Framingham Heart Study. The Journals of Gerontology Series A Biological Sciences and Medical Sciences, 74, 373-379. [Google Scholar] [CrossRef] [PubMed]
[20] Tabara, Y., Kohara, K., Ochi, M., et al. (2016) Association of Of-fice-Based Frailty Score with Hypertensive End Organ Damage in the J-SHIPP Cross-Sectional Study. International Journal of Cardiology, 216, 25-31. [Google Scholar] [CrossRef] [PubMed]
[21] Soysal, P., Stubbs, B., Lucato, P., et al. (2016) Inflammation and Frailty in the Elderly: A Systematic Review and Meta-Analysis. Ageing Research Reviews, 31, 1-8. [Google Scholar] [CrossRef] [PubMed]
[22] Kuang, Z.M. (2020) Effect of Combined Antihypertensive and Li-pid-Lowering Therapies on Cognitive Function: A New Treatment Strategy? Cardiology Research and Practice, 2020, Article ID: 1484357. [Google Scholar] [CrossRef] [PubMed]
[23] Zhang, Y., Li, Y., Wang, R., et al. (2020) Elevated Urinary AD7c-NTP Levels in Older Adults with Hypertension and Cognitive Impairment. Journal of Alzheimer’s Disease, 74, 237-244. [Google Scholar] [CrossRef] 
[24] Walker, K.A., Power, M.C. and Gottesman, R.F. (2017) Defining the Relationship between Hypertension, Cognitive Decline, and Dementia: A Review. Current Hypertension Reports, 19, Article No. 24. [Google Scholar] [CrossRef] [PubMed]
[25] Gabin, J.M., Tambs, K., Saltvedt, I., et al. (2017) Association between Blood Pressure and Alzheimer Disease Measured up to 27 Years Prior to Diagnosis: The HUNT Study. Alz-heimer’s Research & Therapy, 9, Article No. 37. [Google Scholar] [CrossRef] [PubMed]
[26] Swan, G.E., Carmelli, D. and Larue, A. (1998) Systolic Blood Pressure Tracking over 25 to 30 Years and Cognitive Performance in Older Adults. Stroke, 29, 2334-2340. [Google Scholar] [CrossRef] 
[27] Coca, A., Agabiti-Rosei, E., Cifkova, R., et al. (2017) The Polypill in Cardiovascular Prevention: Evidence, Limitations and Perspective—Position Paper of the European Society of Hyper-tension. Journal of Hypertension, 35, 1546- 1553. [Google Scholar] [CrossRef] 
[28] Batal, O., Khatib, O.F., Bair, N., et al. (2011) Sleep Quality, Depression, and Quality of Life in Patients with Pulmonary Hyperten-sion. Lung, 189, 141-149. [Google Scholar] [CrossRef] [PubMed]
[29] Hernández-Aceituno, A., Gual-lar-Castillón, P., García-Esquinas, E., et al. (2019) Association between Sleep Characteristics and Antihypertensive Treatment in Older Adults. Geriatrics & Gerontology International, 19, 537-540. [Google Scholar] [CrossRef] [PubMed]
[30] Kalmbach, D.A. anderson, J.R. and Drake, C.L. (2018) The Impact of Stress on Sleep: Pathogenic Sleep Reactivity as a Vulnerability to Insomnia and Circadian Disorders. Journal of Sleep Research, 27, e12710. [Google Scholar] [CrossRef] [PubMed]
[31] D’Aurea, C., Poyares, D., Piovezan, R.D., et al. (2015) Objective Short Sleep Duration Is Associated with the Activity of the Hypothalamic-Pituitary-Adrenal Axis in Insomnia. Arquivos de Neuro-Psiquiatria, 73, 516-519. [Google Scholar] [CrossRef] 
[32] 赵会颖, 翟晓君, 李岚, 等. 老年高血压患者血压水平与其失眠、抑郁及焦虑状况的相关性[J]. 分子诊断与治疗杂志, 2023, 15(1): 169-172.
[33] Palagini, L., Bruno, R.M., Gemignani, A., et al. (2013) Sleep Loss and Hypertension: A Systematic Review. Current Pharmaceutical Design, 19, 2409-2419. [Google Scholar] [CrossRef] [PubMed]

为你推荐