心外膜脂肪组织及其与房颤关系的研究进展
Research Progress on Epicardial Adipose Tissue and Its Relationship with Atrial Fibrillation
DOI: 10.12677/ACM.2023.1371595, PDF,   
作者: 杨雪松, 侯应龙：山东大学齐鲁医学院，山东 济南；山东第一医科大学第一附属医院(山东省千佛山医院)心内科，山东 济南；李 展, 张玉娇, 任满意：山东第一医科大学第一附属医院(山东省千佛山医院)心内科，山东 济南
关键词: 房颤；心外膜脂肪组织；射频消融；Atrial Fibrillation； Epicardial Adipose Tissue； Radiofrequency Ablation
摘要: 心外膜脂肪组织(EAT)是位于心肌与心包脏层之间的代谢活跃的脂肪库。相比于人体其他内脏脂肪库，EAT不仅具有产热、机械保护的共同特性，还兼有独特分泌功能。研究证实，EAT与房颤的发生及射频消融术后复发相关。EAT导致房颤的机制尚未完全阐明，可能的机制涉及心肌纤维化、脂肪细胞浸润、神经调节失衡等。近年来，EAT受到高度关注，或许会成为预测房颤发生及房颤射频术后复发的一项危险因素。
Abstract: Epicardial adipose tissue (EAT) is an active metabolic fat reservoir located between the myocardi-um and the visceral layer of the pericardium. Compared to other visceral fat reservoirs in the hu-man body, EAT not only has common characteristics of heat production and mechanical protection, but also has unique secretion functions. Research has confirmed that EAT is associated with the oc-currence of atrial fibrillation and recurrence after radiofrequency ablation. The mechanism of EAT leading to atrial fibrillation has not been fully clarified, and the possible mechanism involves myo-cardial fibrosis, adipocyte infiltration, neuromodulation imbalance, etc. In recent years, EAT has received high attention and may become a risk factor for predicting the occurrence and recurrence of atrial fibrillation after radiofrequency surgery.
文章引用：杨雪松, 李展, 张玉娇, 任满意, 侯应龙. 心外膜脂肪组织及其与房颤关系的研究进展[J]. 临床医学进展, 2023, 13(7): 11410-11415. https://doi.org/10.12677/ACM.2023.1371595

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