SII与视网膜静脉阻塞的研究进展
Advances in the Study of SII and Retinal Vein Occlusion
DOI: 10.12677/ACM.2023.1371619, PDF,   
作者: 陈 梅：青海大学研究生院眼科，青海 西宁；余 萍*：青海大学附属医院眼科，青海 西宁
关键词: 视网膜静脉阻塞；炎症生物标志物；系统免疫炎症指数；临床进展；Retinal Vein Occlusion； Inflammatory Biomarkers； Systemic Immune-Inflammatory Index； Clinical Progress
摘要: 视网膜静脉阻塞(retinal vein occlusion, RVO)是仅次于糖尿病性视网膜病变的第二大致盲性的眼底疾病。发病与血管危险因素相关，基于老龄化的发展和慢性病的发病率逐年增长，RVO群体近年呈扩大趋势，使得患者视力受损、生活质量下降、经济负担加重。作为一种异质性疾病，其发病机制复杂，但目前国内外学者普遍认为与机体炎症反应和免疫调节失去平衡相关。本文从结构基础、炎症反应对RVO的病理生理改变进行综述，并着重分析新兴的复合炎症指标——系统免疫炎症指数(systemic immune- inflammation index, SII)在RVO疾病中的临床价值。
Abstract: Retinal vein occlusion (RVO) is the second most blinding fundus disease after diabetic retinopathy. The onset of the disease is associated with vascular risk factors, and based on the development of aging and the increasing incidence of chronic diseases year by year, the RVO population has been expanding in recent years, making the patients’ visual acuity impaired, quality of life reduced, and economic burden increased. As a heterogeneous disease, its pathogenesis is complex, but currently scholars at home and abroad generally agree that it is related to the imbalance of inflammatory re-sponse and immune regulation of the organism. In this paper, we review the pathophysiological changes of RVO from structural basis and inflammatory response, and focus on the clinical value of the emerging composite inflammatory index, systemic immune-inflammation index (SII) in RVO disease.
文章引用：陈梅, 余萍. SII与视网膜静脉阻塞的研究进展[J]. 临床医学进展, 2023, 13(7): 11574-11580. https://doi.org/10.12677/ACM.2023.1371619

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