地佐辛注射液致过敏性休克合并急性肺水肿1例

One Case of Anaphylactic Shock Complicated by Dezocine Injection Combined with Acute Pulmonary Edema

摘要: 分析1例地佐辛注射液致过敏性休克合并急性肺水肿的临床特点和相关因素，为临床安全用药提供参考。1例非哺乳期乳腺炎患者在首次使用地佐辛注射液后，出现面色苍白，大汗淋漓，呼吸急促，血氧饱和度降低、心率加快，意识丧失等症状，随后患者咳粉红色泡沫痰，考虑为药物过敏引起的过敏性休克合并急性肺水肿，经积极抢救后患者痊愈出院。地佐辛注射液为低敏性药物，但临床治疗过程中应警惕罕见的严重不良反应。该病例报道对地佐辛罕见的不良反应做出总结、讨论，以为临床研究提供参考。

Abstract: The clinical characteristics and related factors of acute pulmonary edema complicated by anaphy-lactic shock complicated by dezocine injection were analyzed to provide reference for clinical safety. After using Dezocine injection for the first time, a patient with non-lactating mastitis developed symptoms such as pallor, sweating profusely, shortness of breath, decreased blood oxygen satura-tion, increased heart rate, loss of consciousness, etc. Later, the patient coughed pink foam sputum, which was considered as anaphylactic shock complicated with acute pulmonary edema caused by drug allergy. After active rescue, the patient recovered and was discharged. Dezocine injection is a hypoallergenic drug, but rare serious adverse reactions should be vigilant during clinical treatment. This case report summarizes and discusses the rare adverse effects of dezocine to provide reference for clinical studies.