耦合神经元模型中簇放电的动力学分析
Dynamical Analysis of Bursting in a Coupled-Neuron Model
DOI: 10.12677/DSC.2023.123020, PDF,    科研立项经费支持
作者: 赵雅琪*, 李凤月, 苗 鹏：郑州科技学院基础部，河南 郑州
关键词: pre-B?tzinger复合体；簇放电模式；快慢分析；分岔；pre-B?tzinger Complex； Bursting； Fast-Slow Analysis； Bifurcation
摘要: 呼吸系统是人和动物重要的生理器官之一，位于新生和成年哺乳动物延髓腹外侧区的pre-Bötzinger复合体被认为是呼吸节律产生的中枢，对于研究呼吸系统起着很重要的作用，正常状态和病理状态下呼吸节律有所不同。本文基于pre-Bötzinger复合体耦合神经元模型，利用相平面分析、分岔分析和快慢动力学分析等方法，研究了耦合pre-Bötzinger复合体的簇放电模式及其转迁机制。结果表明钠电导(gNa)对耦合pre-Bötzinger复合体中兴奋性神经元的簇放电节律有重要的影响。
Abstract: Respiratory system is one of the important physiological organs of human and animal. The pre- Bötzinger complex (pre-BötC) is located at a ventrolateral medulla of humans and other mammals, which is considered to be the center for the generation of respiratory rhythms. Respiratory rhythm differs between normal and pathological states, which plays an important role in studying the respiratory system. In this paper, we investigate the bursting and their dynamic mechanisms by phase plane analysis, fast-slow decomposition and bifurcation analysis in coupled-neuron model of the pre-BötC. The results indicate that the Na conductance (gNa) has an important effect on the excitatory neural bursting patterns in the pre-Botzinger complex.
文章引用：赵雅琪, 李凤月, 苗鹏. 耦合神经元模型中簇放电的动力学分析[J]. 动力系统与控制, 2023, 12(3): 186-195. https://doi.org/10.12677/DSC.2023.123020

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