围手术期高压氧联合骨肽治疗对胫骨骨折患者术后康复的影响

Effect of Perioperative Hyperbaric Oxygen Combined with Osteopeptide on Postoperative Rehabilitation of Patients with Tibial Fracture

摘要: 目的：探讨围手术期高压氧联合骨肽治疗对胫骨骨折患者术后康复的影响。方法：选取徐州医科大学附属淮安医院2019年1月~2021年12月期间140例胫骨骨折患者为研究对象，应用随机数字表法分为对照组和试验组，每组70例。对照组在常规治疗基础上，入院时给予骨肽注射液。试验组在对照组治疗的基础上，入院时给予高压氧治疗。结果：试验组术后骨折愈合时间(26.71 ± 3.73)短于对照组(28.33 ± 5.12)，差异有统计学意义(P < 0.05)；试验组术后切口感染、皮缘坏死、延迟愈合、骨不连发生例数均少于对照组，并发症总发生率低于对照组，差异有统计学意义(P < 0.05)。结论：围手术期高压氧联合骨肽治疗可有效促进胫骨骨折愈合，加速术后康复。

Abstract: Objective: To investigate the effect of hyperbaric oxygen combined with osteopeptide on postopera-tive rehabilitation of patients with tibial fracture in perioperative period. Methods: A total of 140 patients with tibial fracture in Huai’an Hospital Affiliated to Xuzhou Medical University from Janu-ary 2019 to December 2021 were selected as research objects, and divided into control group and experimental group by random number table method, with 70 cases in each group. The control group was given bone peptide injection on admission based on routine treatment. On the basis of the control group, the experimental group was given hyperbaric oxygen therapy on admission. Re-sults: The fracture healing time of experimental group (26.71 ± 3.73) was shorter than that of con-trol group (28.33 ± 5.12), and the difference was statistically significant (P < 0.05); the number of cases of postoperative incision infection, cutaneous necrosis, delayed healing and bone nonunion in experimental group was lower than that in control group, and the total incidence of complications was lower, the difference was statistically significant (P < 0.05). Conclusion: Hyperbaric oxygen combined with osteopeptide therapy in perioperative period can effectively promote the healing of tibial fracture and accelerate postoperative rehabilitation.