分泌蛋白Metrnl在糖尿病及其并发症中作用的研究进展
Research Progress on the Role of Secreted Protein Metrnl in Diabetes and Its Complications
摘要: 镍纹样蛋白(Metrnl)是一种新型细胞因子,在人体组织中表达广泛。研究发现,Metrnl与糖尿病及其并发症的发生发展密切相关,如糖尿病肾病(DN)、糖尿病视网膜病变(DR)、糖尿病心肌病(DCM)。但糖尿病患者血清中的Metrnl表达水平仍存在异议,因此,进一步探讨Metrnl在糖尿病及其并发症中的作用及机制,以期加深对脂肪因子Metrnl的认识,为糖尿病及其并发症的诊断和治疗提供新思路。
Abstract: Metrnl is a novel cytokine widely expressed in human tissues. Studies have found that Metrnl is closely related to the occurrence and development of diabetic mellitus and its complications, such as diabetic nephropathy (DN), diabetic retinopathy (DR) and diabetic cardiomyopathy (DCM). How-ever, the expression level of serum Metrnl in diabetic patients is still controversial. Therfore, the role and mechanism of Metrnl in diabetes and its complications are further discussed in order to deepen the understanding of adipokine Metrnl and provide new ideas for the diagnosis and treat-ment of diabetes and its complications.
文章引用:胡梦琳, 何煜暐. 分泌蛋白Metrnl在糖尿病及其并发症中作用的研究进展[J]. 临床医学进展, 2023, 13(8): 12795-12801. https://doi.org/10.12677/ACM.2023.1381794

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