颈动脉易损斑块的CT特征与缺血性脑卒中关系的研究进展
Progress of CT Features of Carotid Vulnerable Plaques in Relation to Ischemic Stroke
DOI: 10.12677/ACM.2023.1381808, PDF,   
作者: 任羿陶：重庆医科大学，重庆；中国科学院重庆绿色智能技术研究院，重庆；中国科学院大学重庆学院，重庆；重庆市人民医院放射科，重庆；李 康*：重庆医科大学，重庆；重庆市人民医院放射科，重庆
关键词: 颈动脉；粥样硬化易损斑块；CT；缺血性脑卒中；Carotid Artery； Atherosclerotic Vulnerable Plaque； CT； Ischemic Stroke
摘要: 缺血性脑卒中具有高死亡率及致残率，严重威胁着患者的生命安全及生活质量。颈动脉粥样硬化易损斑块与缺血性脑卒中事件具有高相关性。CT作为目前临床工作中检测颈动脉斑块的重要方法，对于易损斑块的特征能提供多方面的价值，有助于临床医生对于高危患者制定合适的管理及治疗方案。
Abstract: Ischemic stroke has a high mortality and disability rate, which seriously threatens the life safety and quality of life of patients. Carotid atherosclerotic vulnerable plaques are highly correlated with ischemic stroke events, and CT, as an important method for detecting carotid plaques in clinical practice, provides multiple values for the characterization of vulnerable plaques, which can help clinicians formulate appropriate management and treatment plans for high-risk patients.
文章引用：任羿陶, 李康. 颈动脉易损斑块的CT特征与缺血性脑卒中关系的研究进展[J]. 临床医学进展, 2023, 13(8): 12903-12907. https://doi.org/10.12677/ACM.2023.1381808

参考文献

[1] Che, F., Mi, D., Wang, A., et al. (2022) Extracranial Carotid Plaque Hemorrhage Predicts Ipsilateral Stroke Recurrence in Patients with Carotid Atherosclerosis—A Study Based on High-Resolution Vessel Wall Imaging MRI. BMC Neurology, 22, Article No. 237. [Google Scholar] [CrossRef] [PubMed]
[2] Zhang, L., Li, L., Feng, G., et al. (2021) Advances in CT Techniques in Vascular Calcification. Frontiers in Cardiovascular Medicine, 8, Article ID: 716822. [Google Scholar] [CrossRef] [PubMed]
[3] Singh, A., Nasir, U., Segal, J., et al. (2022) The Utility of Ultra-sound and Computed Tomography in the Assessment of Carotid Artery Plaque Vulnerability—A Mini Review. Fron-tiers in Cardiovascular Medicine, 9, Article ID: 1023562. [Google Scholar] [CrossRef] [PubMed]
[4] Wu, J., He, S., Song, Z., et al. (2023) Macrophage Polarization States in Atherosclerosis. Frontiers in Immunology, 14, Article ID: 1185587. [Google Scholar] [CrossRef] [PubMed]
[5] Grootaert, M. and Bennett, M.R. (2021) Vascular Smooth Mus-cle Cells in Atherosclerosis: Time for a Re-Assessment. Cardiovascular Research, 117, 2326-2339. [Google Scholar] [CrossRef] [PubMed]
[6] Yalcinkaya, M., Fotakis, P., Liu, W., et al. (2023) Cholesterol Accumula-tion in Macrophages Drives NETosis in Atherosclerotic Plaques via IL-1beta Secretion. Cardiovascular Research, 119, 969-981. [Google Scholar] [CrossRef] [PubMed]
[7] Li, J., Zhang, X., Yang, M., et al. (2021) DNA Methylome Profiling Re-veals Epigenetic Regulation of Lipoprotein-Associated Phospholipase A(2) in Human Vulnerable Atherosclerotic Plaque. Clinical Epigenetics, 13, Article No. 161. [Google Scholar] [CrossRef] [PubMed]
[8] Lian, K., White, J.H., Bartlett, E.S., et al. (2012) NASCET Per-cent Stenosis Semi-Automated versus Manual Measurement on CTA. Canadian Journal of Neurological Sciences, 39, 343-346. [Google Scholar] [CrossRef] 
[9] Yaghi, S., de Havenon, A., Rostanski, S., et al. (2021) Carotid Stenosis and Recurrent Ischemic Stroke: A Post-Hoc Analysis of the POINT Trial. Stroke, 52, 2414-2417. [Google Scholar] [CrossRef] 
[10] Pedersen, S.F., Sandholt, B.V., Keller, S.H., et al. (2015) 64Cu-DOTATATE PET/MRI for Detection of Activated Macrophages in Carotid Atherosclerotic Plaques: Studies in Pa-tients Undergoing Endarterectomy. Arteriosclerosis, Thrombosis, and Vascular Biology, 35, 1696-1703. [Google Scholar] [CrossRef] 
[11] Benson, J.C., Savastano, L., Nardi, V., et al. (2021) Intra-plaque CTA Characteristics as Predictors of Symptomatology: A Semiautomated Volumetric Analysis. Emergency Radi-ology, 29, 75-80. [Google Scholar] [CrossRef] [PubMed]
[12] Karlof, E., Seime, T., Dias, N., et al. (2019) Correlation of Computed Tomography with Carotid Plaque Transcriptomes Associates Calcification with Le-sion-Stabilization. Atherosclerosis, 288, 175-185. [Google Scholar] [CrossRef] [PubMed]
[13] Zhao, X., Hippe, D.S., Li, R., et al. (2017) Prevalence and Characteristics of Carotid Artery High-Risk Atherosclerotic Plaques in Chinese Patients with Cerebrovascular Symptoms: A Chinese Atherosclerosis Risk Evaluation II Study. Journal of the American Heart Association, 6, e005831. [Google Scholar] [CrossRef] 
[14] Jain, K., Arun, P.B., Sreedharan, S.E., et al. (2022) Studying Plaque Characteristics in Extracranial Carotid Artery Disease Using CT Angiography—Risk Predictors beyond Luminal Stenosis. Clinical Neurology and Neurosurgery, 222, Article ID: 107420. [Google Scholar] [CrossRef] [PubMed]
[15] Wasserman, B.A., Smith, W.I., Trout, H.R., et al. (2002) Ca-rotid Artery Atherosclerosis: In Vivo Morphologic Characterization with Gadolinium-Enhanced Double-Oblique MR Imaging Initial Results. Radiology, 223, 566-573. [Google Scholar] [CrossRef] [PubMed]
[16] Rafailidis, V., Chryssogonidis, I., Tegos, T., et al. (2017) Imaging of the Ulcerated Carotid Atherosclerotic Plaque: A Review of the Literature. Insights into Imaging, 8, 213-225. [Google Scholar] [CrossRef] [PubMed]
[17] 张圆圆, 孟秀君, 田沈, 等. 颈部彩色多普勒超声、CT血管成像与数字减影血管造影诊断颈内动脉狭窄、斑块形态及溃疡的准确性比较[J]. 中国全科医学, 2015, 18(30): 3763-3768.
[18] Ha, S.M., Suh, S.I., Seo, W.K., et al. (2016) Arterial Wall Imaging in Symptomatic Carotid Stenosis: Delayed Enhancement on MDCT Angiography. Neurointervention, 11, 18-23. [Google Scholar] [CrossRef] [PubMed]
[19] Korn, A., Bender, B., Schabel, C., et al. (2015) Dual-Source Dual-Energy CT Angiography of the Supra-Aortic Arteries with Tin Filter: Impact of Tube Voltage Selection. Academic Radiology, 22, 708-713. [Google Scholar] [CrossRef] [PubMed]
[20] Lu, S.S., Ge, S., Su, C.Q., et al. (2018) MRI of Plaque Characteris-tics and Relationship with Downstream Perfusion and Cerebral Infarction in Patients with Symptomatic Middle Cerebral Artery Stenosis. Journal of Magnetic Resonance Imaging, 48, 66-73. [Google Scholar] [CrossRef] [PubMed]

为你推荐