CD4+T细胞在风湿病外周血中的变化研究进展
Update on Peripheral CD4+T-Cell Changes in Rheumatic Diseases
DOI: 10.12677/ACM.2023.1381828, PDF,   
作者: 严丽芳:青海红十字医院风湿免疫科,青海 西宁
关键词: 风湿病CD4+T细胞变化研究进展Rheumatic Diseases CD4+T-Cell Change Research Progress
摘要: 免疫学方面的研究已经证实CD4+T细胞及其分化亚群参与大多数风湿病的发病机制,与器官受累、治疗反应密切相关,但在不同的风湿病中,CD4+T细胞具体是如何分化的,关于这些的研究目前还并不充分,为此,对近年来CD4+T细胞的主要分化亚群(Th1/Th2/Th17和Treg细胞)在常见风湿病当中的研究情况作一综述。
Abstract: It has been evidenced that CD4+T-cell and their products have been associated with the pathology, organ involvement, or therapeutic response of some CTDs in several researches from immunology, but how exactly CD4+T cells differentiate in different rheumatic diseases is not well studied. In this review, the author would like to summarize changes in peripheral T-cell subsets in CTDs, especially focusing on differences in CD4+T-cell subpopulations-Th1 cell, Th2 cell, Th17 cell and Treg cell.
文章引用:严丽芳. CD4+T细胞在风湿病外周血中的变化研究进展[J]. 临床医学进展, 2023, 13(8): 13050-13056. https://doi.org/10.12677/ACM.2023.1381828

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