斑马鱼模型用于人类慢性病研究进展
Research Progress of Zebrafish Models for Human Chronic Diseases
摘要: 慢性病是一类长期发展并持续存在的疾病,主要包括心血管疾病、糖尿病、肿瘤以及神经系统疾病等。随着近年来人口老龄化的加剧,慢性病给个体健康和社会经济带来了巨大的负担和挑战,而开展各种慢性病发病机制和新型治疗方法的研究显得至关重要。斑马鱼是一种模式生物,近年来开始用于遗传发育生物学、人类疾病、环境毒理学和药理学等领域的研究。本文归纳了斑马鱼模型在糖尿病、多发性骨髓瘤和神经系统疾病研究中的进展。
Abstract: Chronic diseases are a class of long-term development and persistent diseases, mainly including cardiovascular diseases, diabetes, tumors and neurological diseases. With the increase of popula-tion aging in recent years, chronic diseases have brought huge burden and challenge to individual health and social economy, and it is very important to carry out research on the pathogenesis of various chronic diseases and new treatment methods. Zebrafish is a model organism that has been used in recent years in the fields of genetic developmental biology, human disease, environmental toxicology and pharmacology. This paper summarizes the progress of zebrafish model in the re-search of diabetes, multiple myeloma and nervous system diseases.
文章引用:梁钰, 吴亮. 斑马鱼模型用于人类慢性病研究进展[J]. 临床医学进展, 2023, 13(8): 13289-13296. https://doi.org/10.12677/ACM.2023.1381857

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