宫颈上皮内病变患者锥切术后切缘阳性的相关研究

Study on Positive Margin after Conical Resection in Patients with Cervical Intraepithelial Lesions

摘要: 宫颈上皮内病变(CIN)是宫颈癌的癌前病变，目前治疗CIN的方法包括宫颈冷刀锥切术(cold-knife conization, CKC)、宫颈环形电切术(loop electrosurgical excision procedure, LEEP)和冷冻治疗。CKC是目前治疗高级别鳞状上皮内病变的首选方式。由于宫颈锥切术并不是全部将宫颈予以切除，锥切术后难免会出现切缘阳性的可能，因此锥切术后切缘阳性问题成为临床医生关注的焦点。对于初次锥切术后病理证实切缘阳性的宫颈高级别鳞状上皮内病变患者的进一步处理是采取积极措施还是保守治疗，严密随访，目前仍没有统一的标准。因此，宫颈锥切的切缘阳性问题越来越受到更多医生及患者的关注。

Abstract: Cervical intraepithelial lesion (CIN) is cervical precancerous lesions of cerviacal cancer, the current treatment methods of CIN include cervical cold knife cut method (cold-knife conization, CKC), cervi-cal loop electricity cut method (loop electrosurgical excision procedure, LEEP) and cryotherapy. CKC is currently the preferred treatment for high-level squamous intraepithelial lesions. Because not the whole cervix is completely removed in conical excision, it is inevitable that there will be a posi-tive margin after conical excision, so the problem of positive margin after conical excision has be-come the focus of clinicians. At present, there is still no unified standard for the further manage-ment of high-level squamous intraepithelial lesions of the cervix with positive incisal margin con-firmed by pathology after the initial coning operation, whether to adopt active measures or con-servative treatment or strict follow-up. Therefore, the positive margin of cervical conectomy has at-tracted more and more attention from more doctors and patients.