自身免疫性甲状腺疾病对妊娠结局影响研究进展
Research Progress on the Influence of Autoimmune Thyroid Disease on Pregnancy Outcome
DOI: 10.12677/ACM.2023.1381917, PDF,   
作者: 李 敏, 郭 鑫, 袁 婷:西安医学院研究生工作部,陕西 西安;魏君香, 贺译平*:西北妇女儿童医院产科,陕西 西安
关键词: 甲状腺自身抗体甲状腺自身免疫妊娠结局新生儿结局Thyroid Autoantibody Thyroid Autoimmunity Pregnancy Outcome Offspring Outcome
摘要: 近年来,随着我国政策开放,高龄产妇逐渐增加,妊娠期甲状腺疾病发病率也逐年上升。而妊娠期甲状腺自身免疫不仅关系母体健康,还与妊娠结局相关,影响母儿健康。甲状腺自身抗体阳性预示着易发生自身免疫性甲状腺疾病,而甲状腺自身抗体包括甲状腺过氧化物酶抗体(TPOAb)、甲状腺球蛋白抗体(TGAb)及促甲状腺激素受体抗体(TRAb)等,其可一种或者多种同时存在于体内,但应用最为广泛的为TPOAb和TGAb。目前国内外对于自身免疫性甲状腺疾病与妊娠结局关系仍然存在部分争议。本研究结合近几年国内外关于自身免疫性甲状腺疾病相关因素与对妊娠结局影响的研究进展进行综述。
Abstract: In recent years, with the opening of China’s policy, the number of advanced maternal age has grad-ually increased, and the incidence rate of Thyroid disease during pregnancy has also increased year by year. Thyroid autoimmunity during pregnancy is not only related to maternal health, but also to pregnancy outcomes, affecting maternal and fetal health. Positive thyroid Autoantibody indicates that autoimmune Thyroid disease is prone to occur, and thyroid Autoantibody includes Thyroid peroxidase antibody (TPOAb), thyroglobulin antibody (TGAb) and Thyrotropin receptor antibody (TRAb), which can exist in one or more simultaneously in the body, but the most widely used are TPOAb and TGAb. At present, there are still some disputes about the relationship between auto-immune Thyroid disease and pregnancy outcome at home and abroad. This study reviewed the re-search progress on the related factors of autoimmune Thyroid disease and its influence on preg-nancy outcome in recent years.
文章引用:李敏, 魏君香, 郭鑫, 袁婷, 贺译平. 自身免疫性甲状腺疾病对妊娠结局影响研究进展[J]. 临床医学进展, 2023, 13(8): 13720-13728. https://doi.org/10.12677/ACM.2023.1381917

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