原发性脑出血早期血肿扩大的影响因素分析
Analysis of Influencing Factors of Early Hematoma Enlargement in Primary Cerebral Hemorrhage
DOI: 10.12677/ACM.2023.1391935, PDF,   
作者: 王子鹤：内蒙古民族大学第二临床医学院，内蒙古 通辽；王 伟：内蒙古林业总医院行政部门，内蒙古 呼伦贝尔
关键词: 原发性脑出血；高血压；血肿扩大影响因素；Primary Cerebral Hemorrhage； Hypertension； Influencing Factors of Hematoma Enlargement
摘要: 血肿扩大在原发性脑出血早期患者中并不罕见，是一种十分严重的并发症，同时，它也预示着患者不良的预后。早期血肿增大通常定义为复查CT扫描血肿体积对比首次发现时增大33%。到目前为止，还没有理想的动物模型可以模拟早期血肿生长的确切病理生理过程。新的影像学预测指标如CT血管造影斑点征象和CT混合征象可以预测脑出血患者早期血肿的生长。监测和调节血压可以改善预后。脑出血患者早期迅速的降低血压(收缩压至<140 mmHg)大概率是安全的。本文综述了原发性脑出血早期血肿扩大的定义、病理生理学、危险因素和旨在改善预后的新治疗方案。
Abstract: Hematoma enlargement is not uncommon in patients with primary cerebral hemorrhage. It is a very serious complication and it also indicates poor prognosis of patients. Early hematoma en-largement is usually defined as a 33% increase in hematoma volume compared with the first dis-covery on CT scan. Up to now, no animal model can simulate the exact pathophysiology of early he-matoma growth. New imaging predictors, such as CT angiographic speckle signs and CT mixed signs, can predict the growth of early hematoma in patients with cerebral hemorrhage. Monitoring and regulating blood pressure can improve prognosis. Early rapid blood pressure (systolic blood pres-sure to <140 mmHg) in patients with cerebral hemorrhage is probably safe. This article reviews the definition, pathophysiology, risk factors, and new treatment options aimed at improving prognosis of early hematoma enlargement in primary cerebral hemorrhage.
文章引用：王子鹤, 王伟. 原发性脑出血早期血肿扩大的影响因素分析[J]. 临床医学进展, 2023, 13(9): 13843-13848. https://doi.org/10.12677/ACM.2023.1391935

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