颞叶癫痫共患人格障碍的研究进展

Research Progress of Temporal Lobe Epilepsy Comorbidity Personality Disorder

摘要: 颞叶癫痫(Temporal lobe epilepsy, TLE)是最常见的局灶性癫痫类型，其共患疾病越来越引起重视，其中TLE共患精神疾病非常普遍，人格改变是TLE较为常见的共患精神疾病，其进一步恶化了癫痫的结局，加重了患者及其社会的负担。目前，颞叶癫痫共患人格障碍存在高发病率、低诊断率、低治疗率的现象，TLE共患人格障碍的筛查、评估、管理和治疗应成为临床不可或缺的组成部分。本文对目前TLE共患人格障碍研究进展(流行病学、危险因素、潜在机制、临床表现、治疗等方面)进行回顾，希望推动TLE共患人格障碍的认识和治疗。

Abstract: Temporal lobe epilepsy (TLE) is the most common type of focal epilepsy, and its comorbidity has at-tracted more and more attention. In TLE, comorbidity of mental illness is very common, and per-sonality change is a more common comorbidity of mental illness, which further worsens the out-come of epilepsy. This increases the burden on patients and their society. At present, temporal epi-lepsy comorbidity personality disorder has high incidence, low diagnosis rate and low treatment rate. Screening, evaluation, management and treatment of TLE comorbidity personality disorder should become an indispensable part of clinical practice. This article reviews the current research progress of TLE comorbidity personality disorder (epidemiology, risk factors, potential mechanisms, clinical manifestations, treatment, etc.), hoping to promote the understanding and treatment of TLE comorbidity personality disorder.